A unique myosin heavy chain cDNA (AMHC1), which is expressed exclusively in the atria of the developing chicken heart, was isolated and used to study the generation of diversified cardiac myocyte cell lineages. The pattern of AMHC1 gene expression during heart formation was determined by whole-mount in situ hybridization. AMHC1 is first activated in the posterior segment of the heart when these...

An imaging system for di-4-ANEPPS (4-[beta-[2-(di-n-butylamino)-6-naphthylvinyl]pyridinium]) voltage-sensitive dye recordings has been adapted for recording from an in vitro mouse heart preparation that consists of both atria in isolation. This approach has been used to study inter- and intra-atrial activation and conduction and to monitor action potential durations (APDs) in the left and right...

Ciliary neurotrophic factor (CNTF) has been implicated in the development, survival, and maintenance of a broad range of neurons and glia in the peripheral nervous system and the CNS. Evidence also suggests that CNTF may affect development of cells outside the nervous system. We have found that functional CNTF and its receptor are expressed in developing embryonic chick heart and may be involve...

Heart contains a variety of neurons known to influence cardiac functions. Little is known about the neurochemistry of these neurons. In this study, neurochemistry of intra cardiac neurons of the intrinsic cardiac ganglia was investigated. The technique used allows studying the morphology of the ganglionated nerve plexus found within the atria and great cardiac vessels as well as of individual n...

The Chinese alligator (Alligator sinensis) belongs to the genus Alligator, which is a unique crocodile in China. In order study macroscopic structure of heart alligator, we performed detailed cardiac anatomy on five specimens. cranial mediastinum. It caudally involved by liver margins, and ventrally ribs, intercostal muscles, sternum dorsally lungs. wild typical four-chamber heart, with two (ri...

The P wave and Psi-loop were derived from coplanar outlines of the contour of seven human atria, including left atrial enlargement, in which it was assumed that the process of depolarization spread in a radial fashion from the sinoatrial node. The "derived" planar projections of the P waves of the standard leads and Psti-loops were similar in relative amplitude and general contour to those reco...

The heart begins simply as a bilateral field within the lateral plate mesoderm (Figure 1.1, Table 1.1). As the early embryo undergoes formation of the gut-tube, these bilateral fields migrate toward the midline, where the cranial-most aspect of the fields will fuse ventrally to form the outer curvature of the heart tube.1 These fields will continue to migrate together, with more of the heart fi...

Atrial natriuretic peptide (ANP) is produced and released by mammalian cardiomyocytes and induces natriuresis, diuresis, and lowering of blood pressure. The present study examined localization of ANP and a possible role of the hypothalamic-pituitary-adrenal axis (HPA) activity on the expression of proANP gene in the heart. The Sprague Dawley (SD) and Lewis (LE) rat strains were used. The animal...