نتایج جستجو برای: hdlc

تعداد نتایج: 464  

2017
Rajaragupathy Sujatha Subramanian Kavitha

Background: Stroke makes a significant cause of morbidity and mortality worldwide. Although derangements in the lipid profile have been suggested as a risk factor for the development of stroke, various studies show inconsistent results on the association between lipid profile and stroke. A very few studies have commented on the status of lipid indices in stroke patients. Methods: After obtainin...

Journal: :Stroke 2002
Thomas B Clarkson Mary S Anthony Tomi S Mikkola Richard W St Clair

BACKGROUND AND PURPOSE Tibolone is a tissue-specific compound that has favorable effects on bone and menopausal symptoms without stimulating endometrium or breast, but lowers concentrations of plasma high-density lipoprotein (HDL) cholesterol (HDLC). This study was designed to determine whether the HDL lowering with tibolone exacerbated common or internal carotid artery atherosclerosis and to e...

2007
Hongkeun Cho

Despite the excellent success of lowering low-density lipoprotein cholesterol (LDLc) cholesterol for treating coronary heart disease (CHD), a major part of the population still suffer from CHD. This fact is more prominent among the high risk patients who receive lipid lowering treatment with statins. This treatment is based on the prevailing view that LDL cholesterol (LDLc) is the only importan...

Journal: :Sindh University research journal 2021

Present study compares the potential of Ficus carica and Allium sativum on triglyceride to HDL ratio in high fat diet fed male Wistar albino rats. A sample 36 rats was randomly divided into 6 groups (A, B, C, D, E F). Hyperlipidemia induced by (HFD) (banaspati ghee + coconut oil) mixed normal chow diet. After six weeks, blood taken through retro – orbital capillary plexus, centrifuged get sera,...

Journal: :JPMA. The Journal of the Pakistan Medical Association 1997
V Singh S A Zaidi V S Singh

Serum and biliary lipoproteins, total cholesterol (Tc) and triglycerides (TG) were measured in patients with gallstones and in those without gallstones. Serum and biliary LDLc, TG and Tc were significantly higher (P < 0.001) in cases having gall stones than those without stones while HDLc were low (P < 0.001) in those with stones. No difference was found in very low density lipoproteins (VLDLc)...

Journal: :Arteriosclerosis, thrombosis, and vascular biology 2009
Remco Franssen Raaj R Sankatsing Elly Hassink Barbara Hutten Mariette T Ackermans Kees Brinkman René Oesterholt Alejandro Arenas-Pinto Stephen P Storfer John J Kastelein Hans P Sauerwein Peter Reiss Erik S Stroes

OBJECTIVE The purpose of this study was to investigate the mechanism by which the nonnucleoside reverse transcriptase inhibitor (NNRTI) nevirapine (NVP) increases high-density lipoprotein cholesterol (HDLc) in treatment-experienced human immunodeficiency virus-1 (HIV-1)-infected patients. METHODS AND RESULTS Twelve HIV-1 infected patients, with stably suppressed HIV-1 viral load using AZT/3TC...

Journal: :Circulation 1998
M E Wittekoek S N Pimstone P W Reymer L Feuth G J Botma J C Defesche M Prins M R Hayden J J Kastelein

BACKGROUND Recently, a mutation in the lipoprotein lipase (LPL) gene (N291S) has been reported in 2% to 5% of individuals in western populations and is associated with increased triglyceride (TG) and reduced HDL cholesterol (HDLC) concentrations. METHODS AND RESULTS Here we report a significant alteration in biochemical and clinical phenotype in subjects with familial hypercholesterolemia (FH...

2009
Remco Franssen Raaj R. Sankatsing Elly Hassink Barbara Hutten Mariette T. Ackermans Kees Brinkman René Oesterholt Alejandro Arenas-Pinto Stephen P. Storfer John J. Kastelein Hans P. Sauerwein Peter Reiss Erik S. Stroes

Objective—The purpose of this study was to investigate the mechanism by which the nonnucleoside reverse transcriptase inhibitor (NNRTI) nevirapine (NVP) increases high-density lipoprotein cholesterol (HDLc) in treatment-experienced human immunodeficiency virus-1 (HIV-1)–infected patients. Methods and Results—Twelve HIV-1 infected patients, with stably suppressed HIV-1 viral load using AZT/3TC/ ...

2015
Yael Baumfeld Lena Novack Arnon Wiznitzer Eyal Sheiner Yakov Henkin Michael Sherf Victor Novack Antonio Gonzalez-Bulnes

INTRODUCTION The association between glucose intolerance, elevated blood pressure and abnormal lipid levels is well established and comprises the basis of metabolic syndrome pathophysiology. We hypothesize that abnormal preconception lipid levels are associated with the increased risk of severe pregnancy complications such as preeclampsia and gestational diabetes mellitus. METHODS We included...

Journal: :American journal of physiology. Gastrointestinal and liver physiology 2009
Mark J Evans Paige E Mahaney Lisa Borges-Marcucci KehDih Lai Shuguang Wang Julie A Krueger Stephen J Gardell Christine Huard Robert Martinez George P Vlasuk Douglas C Harnish

The nuclear hormone receptor farnesoid X receptor (FXR) plays a critical role in the regulation of bile acid, triglyceride (TG), and cholesterol homeostasis. WAY-362450 (FXR-450/XL335) is a potent synthetic FXR agonist as characterized in luciferase reporter assays and in mediating FXR target gene regulation in primary human and immortalized mouse hepatocytes. In vivo, WAY-362450 dose dependent...

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