Background: Hepatitis B virus (HBV) and hepatitis C virus (HCV) infections are the main causes of severe liver failure worldwide. This study was conducted to evaluate the incidence rate and trend of these infections over six successive years from 2008 to 2013 in Ilam Province, western Iran. Methods: We studied the registered data of HBV and HCV based on the National Notifiable Diseases Surveil...

background: nowadays, the immune response to hepatitis c (hcv) treatment has become a crucial issue mostly due to the interleukin 28b (il-28b) polymorphism effects in chronic hcv patients. the aim of this study was to detect the polymorphism of il-28b gene (rs12979860) in hcv genotype 1 patients treated with pegylated interferon and ribavirin. methods: from the 2010 to 2012, a total of 115 peri...

conclusions polymorphism in the hemochromatosis gene may confer some degree of risk for hcv infection, and individuals carrying the h and c alleles may be susceptible to this disease; however, a larger sample of hcv patients and healthy individuals may be necessary to further illustrate the role of these polymorphisms in hcv. patients and methods hfe gene polymorphisms were examined in a total ...

BACKGROUND Human immunodeficiency virus (HIV) infection leads to more rapid progression of hepatitis C virus (HCV)-related liver fibrosis, which could be linked to differences in the severity of liver inflammation among HIV/HCV co-infected individuals compared to HCV mono-infected individuals. This study assessed the association of HIV co-infection with pro-inflammatory and pro-fibrogenic cytok...

objective: hepatitis c virus (hcv) is one of the most relevant persistent infections afflicting the human population. control of viral replication in hcv infection has been associated with the cellular component of the host immune response. several mechanisms have been proposed to explain this abnormal immune response, among them an altered activity of regulatory t cells (tregs) being the most ...

Introduction. In Poland, approximately 2% of the total population is infected with hepatitis C virus (HCV) (estimated at 730,000 people). HCV an etiologic factor chronic C. Hepatitis a disease which, when untreated, may lead to cirrhosis liver and/or primary cancer. 
 Objective. The aim study was analysis personal medical history patient hepatocellular cancer from aspect infection HCV.&#x0...

background : hepatitis b virus (hbv) and hepatitis c virus (hcv) infections are major global public health problems. this study was conducted to investigate the incidence rate of these infections over six successive years in hamadan province, the west of iran. methods: this retrospective cohort study was conducted on the database of hepatitis registry. in this study, 1257 subjects infected by h...

Hepatitis C virus (HCV) is a positive-stranded RNA virus that infects approximately 130-170 million people worldwide. In 2005, the first HCV infection system in cell culture was established using clone JFH-1, which was isolated from a Japanese patient with fulminant HCV infection. JFH-1 replicates efficiently in hepatoma cells and infectious virion particles are released into the culture supern...

background: various infectious agents like ebstein barr virus (ebv), htlv-1 and helicobacter pylori have known as etiologic factors in different sub-types of lymphoma. although hepatitis c virus (hcv) has not only been important for its hepatotropism and hepatitis development, but also in recent years its association with some forms of non- hodgkin’s lymphoma (nhl), especially b cell nhl, has r...

Through living-donor liver transplantation (LDLT) from a human leukocyte antigen (HLA)-matched sibling donor, it may be possible to stop the use of immunosuppressants. It is that acute antibody-mediated rejection and chronic active through positivity donor-specific anti-HLA antibodies and/or T cell-mediated affect prognosis transplantation. The etiologies diseases recipient also post-transplant...