The seroprevalence and genotypes of hepatitis C virus (HCV) were studied in 283 patients attending six haemodialysis units in Jordan. In all, 98 (34.6%) patients were anti-HCV-positive by EIA, 92 (93.9%) of whom were also reactive in an immunoblot assay. The prevalence of anti-HCV was correlated with a history of blood transfusion before the introduction of blood donor screening for HCV and wit...

BACKGROUND It has been proposed that hepatitis C virus (HCV)-infected patients with end-stage renal disease undergoing maintenance haemodialysis may lack HCV antibody (anti-HCV) despite chronic HCV viraemia. This carries important implications for the design of surveillance policies. METHODS To characterize the prevalence of antibody-negative/RNA-positive HCV infection, patients attending sev...

Objective: To evaluate hepatitis B and C serology findings to determine the current prevalence of those who had applied Turkish hospital in Mogadishu, Somalia. Material Method : The demographic test results (HBsAg, antiHBs antibody, anti-HCV) patients were recorded retrospectively from their files. Results: A total 152,266 patients, 75,903 (49.8%) male 76,363 (50.2%) female, with a mean age 34 ...

high prevalence of hbv and hcv infections in prisoners suggests them as one of the main infection source in community. preventive measures can possibly decrease their rate of infection and infectivity. we evaluated prevalence of hbv and hcv infections and their relation to dangerous behavior in addict prisoners. this was a cross-sectional study included prisoners of central provinces of iran wh...

Background.  Perinatally acquired hepatitis C virus (HCV) is the main source of pediatric HCV infection. However, the best time for initiation of screening and follow up of these infants is still unknown. Analysis of the clinical data of infants born to HCV-infected mothers, transmission rates, and pathway of HCV testing could be important for optimization of their management. Methods.  Childre...

BACKGROUND Detectable HCV-specific cellular immune responses in HCV antibody and RNA negative people who inject drugs (PWID) raise the question of whether some are resistant to HCV infection. Immune responses from people who have been exposed to hepatitis C virus (HCV) and remain anti-HCV negative are of interest for HCV vaccine development; however, limited research addresses this area. OBJE...

Background and Aims: The hepatitis C virus (HCV) F protein is a recently described, frameshift product of HCV core encoding sequence. Its function and antigenic properties are unknown. In order to assess the presence of antibodies specific for F protein we characterized specific anti-F antibodies in patients with chronic HCV infection. Methods: The F protein was cloned from the HCV genome....

Abstract Globally, approximately 1.5 million new Hepatitis C virus (HCV) infections occur annually. A vaccine to prevent chronic HCV infection would limit transmission and pathogenesis of HCV. To understand immunity in high risk populations, we prospectively followed antibody negative high-risk people who inject drugs (PWIDs) a protocol designed for monthly follow-up. We demonstrated previously...

BACKGROUND The measurement of anti-HCV antibodies using immunological methods and the confirmation of viral nuclear acid based on molecular methods is important in diagnosis and follow-up of the HCV infection. OBJECTIVES In this study, we aimed to analyse HCV core Antigen positivity among anti-HCV antibody positive sera to determine the significance of testing of HCV core Ag for the laborator...