INTRODUCTION To identify the differences in a socioeconomic profile between two cohorts of diabetic patients - one with diabetic foot problems and another without diabetic foot problems. MATERIALS AND METHODS The cohort with diabetic foot problems (including cellulitis, abscess, osteomyelitis, septic arthritis, gangrene, ulcers, or Charcot joint disease) consisted of 122 diabetic patients, wh...

BACKGROUND Recent studies on the variants in duplicated human alpha globin genes (HBA2 and HBA1) actively target the α-globin gene as molecular modulators for the treatment of β-thalassemia major. Identification of the exact position of variant in HBA1, HBA2 or its patchworks is mandatory to support the therapeutic aims in β-thalassemia major, by identifying specific modulators for the reactiva...

Anyone who has looked through sequential outpatient clinic letters will be in no doubt in which area the next major improvement in management of diabetes will transpire. The procrastination of positive action until the HbA1, result is available, often in conjunction with seemingly favourable home blood glucose monitoring data, renders the measurement almost useless unless the patient is seen ag...

Sympathetic function was studied in 101 diabetic children and 102 age and sex matched control children, as part of a longitudinal study of the evolution of microvascular disease in the population of diabetic children and adolescents in Avon County. The median (range) age of the diabetic population was 13.5 (6.0-17.2) years, the duration of diabetes was 4.0 (0.4-13.9) years, and glycated haemogl...