7.11.5.1 Thermal and Photochemical Reactions 405 7.11.5.2 Reactions with Electrophiles 406 7.11.5.2.1 N-Alkylation 406 7.11.5.2.2 C-Allcylation and arylation 408 7.11.5.2.3 Reaction with diazonium ions 409 7.11.5.2.4 Oxidation of ring atoms 409 7.11.5.2.5 Halogenation 410 7.11.5.2.6 Metal complexes 410 7.11.5.3 Reactions with Nucleophiles 411 7.11.5.3.1 Reduction 411 7.11.5.3.2 Amination and hy...

Regioselective halogenation of the terminal isopropylidene unit of different acyclic polyolefinic polyprenoids (farnesyl acetate, geranylgeranyl acetate, squalene, etc.) using NCS/catalytic polymer-supported selenenyl bromide is described; good to excellent yields are obtained (68-96%). The first applications of this protocol include the concise synthesis of bioactive terpenoids 1-3.

A chiral anion phase-transfer system for enantioselective halogenation is described. Highly insoluble, ionic reagents were developed as electrophilic bromine and iodine sources, and application of this system to o-anilidostyrenes afforded halogenated 4H-3,1-benzoxazines with excellent yield and enantioselectivity.

The original composition of Laguocuo Salt Lake was found in the mirabilite area 15 °C isothermal phase diagrams Li+, Na+, K+//Cl−, SO42−-H2O system. Four phases comprise evaporation procedure. first stage is unsaturated except for carbonate. second made up sodium chloride, mirabilite, and borax precipitate simultaneously, where halogenation rate 31.58%, water loss 68.32%. penultimate step lithi...

The ubiquity of carbon halogen bonds in the structural core numerous biomolecules and pharmaceuticals along with their role as synthetic precursors various organic reactions makes halides a crucial class compounds. Consequently, synthesis high regioselectivity is paramount importance chemistry. In nature, selective halogenation achieved by metalloenzymes efficiency involving high-valent iron-ox...