The DNA helices are taken as the canonical B-form and are produced from the previously developed grooved primitive model [1]. The grooved primitive model retains a high degree of realistic helical structure and phosphate charge distribution of DNA [2], and is tractable for analytical statistical mechanical theories [3]-[5]. We use the B-form DNA helix since it is the most common and stable form...

micromixers are one of the most crucial components of lab-on-a-chip devices with the intention of mixing and dispersion of reagents like small molecules and particles. the challenge facing micromixers is typically insufficient mixing efficiency in basic designs, which results in longer microchannels. therefore, it is desirable to increase mixing efficiency, in order to decrease mixing length, w...

A pressure-based computational fluid dynamics (CFD) code is employed to calculate the flow field and rotordynamic forces in a whirling, grooved liquid annular seal. To validate the capabilities of the CFD code for this class of problems, comparisons of basic fluid dynamic parameters are made to three-dimensional laser Doppler anemometer (LDA) measurements for a spinning, centered grooved seal. ...

This study evaluated in vitro the differences in morphological behaviour between fibroblast cultured on smooth and microgrooved substrata (groove depth: 0.5 microm, width: 1, 2, 5, and 10 microm), which were subjected to simulated microgravity. The aim of the study was to clarify which of these parameters was more dominant to determine cell behaviour. Morphological characteristics were investig...

[Purpose] The purpose of this study was to investigate the difference in task performance, grip and pinch strength, and dexterity with and without cock-up splints, which are widely used in occupational therapy practice. [Methods] Twenty-three participants performed Jebsen-Taylor hand function test and grooved pegboard for task performance and dexterity. The power grip and pinch strength was mea...

OBJECTIVE Neuropsychological dysfunction is common in patients with idiopathic normal pressure hydrocephalus (iNPH). Shunt treatment is beneficial, some patients reaching complete or almost complete recovery, while others show only minor improvement. We aimed to assess the efficacy of a small selection of well characterized and sensitive neuropsychological tests in the context of the European m...

Circulating tumor cells (CTCs) in peripheral blood have been recognized as a general biomarker for diagnosing cancer and providing guidance for personalized treatments. Yet due to their rarity, the challenge for their clinical utility lies in the efficient isolation while avoiding the capture of other non-targeted white blood cells (WBCs). In this paper, a wavy-herringbone (HB) microfluidic chi...

Olfactory receptors in basiconic and grooved-peg sensilla on the antenna of fifth-instar Triatoma infestans nymphs respond to host odours. Gas chromatography analyses of host odour extracts coupled to electrophysiological recordings from basiconic sensillum receptors indicate that nonanal is a constituent of sheep wool and chicken feather odour that stimulates one of the receptors in this type ...

Contact guidance refers to the reactions of cells with the topography of their substratum. Current hypotheses on the mechanism of contact guidance focus on the dynamic behaviour of the cytoskeletal components, but most observations have been made on cells that have already become oriented with topographic features of the substratum. The purpose of this study was to examine the sequence in which...