In one study, 287 patients diagnosed with asymptomatic carotid plaques or abnormal plaque free carotid intima-media thickness (CIMT) were randomly assigned to a GSE group (n = 146) or control group (n = 141). As anticipated, after treatment, GSE resulted in significant reduction in MMCIMT progression, while MMCIMT and plaque score were stable and even increased with the control group. The numbe...

background fluoxetine (flx), a selective serotonin reuptake inhibitor, is widely used in the treatment of neurological disorders. however, its application carries the risk of adverse reactions, including reproductive toxicities. grape seed is highly regarded for its pharmacological activities, specifically its antioxidant properties. objectives this study was designed to evaluate whether hydroa...

background: the current study tried to investigate the antioxidant and anti-bacterial effects of green tea and grape seed extract (with a volume of 2%) on durability of tilapia packed in polyethylene bags, which were kept in cool temperature of 4±1 °c. methods: prepared fish were divided into 3 batches: 2 batches were treated by dipping for 30 min in ethanolic of green tea extract (2% v/v) and ...

The aims of this study were to investigate the effects of hesperidin, a citrus flavonoid, on human root dentin demineralization and collagen preservation, and compare it with chlorhexidine and grape seed extract. Specimens were assigned to different treatment groups: hesperidin, chlorhexidine and grape seed extract. Specimens were subjected to pH cycling by demineralization for 14 h, incubation...

The major polyphenols in grape seed have been shown to have beneficial health effects in the prevention of dyslipidemia and cardiovascular diseases. In this present study, we investigated the cholesterol-lowering activity of three major polyphenolic compounds found in grape seed. The results showed that gallic acid, catechin, and epicatechin significantly inhibited pancreatic cholesterol estera...

grape seed proanthocyanidin (gsp) bears a very powerful antioxidant effects. studies demonstrated that proanthocyanidins protect against free radicals mediated cardiovascular and renal disorders. the present study was designed to assess the effect of gsp on the heart of diabetic rats. forty rats were divided into four groups of 10 animals each: group i: control, group ii: control group were giv...

conclusions in conclusion, taking gse for eight weeks had beneficial effects on the plasma gsh, mda levels, and markers of insulin metabolism of female volleyball players. results supplementation with gse resulted in a significant rise in the plasma glutathione (gsh) level (+265.5 ± 344.2 vs. +2.2 ± 378.2 µmol/l, p = 0.02), as well as a significant decrease in the malondialdehyde (mda) level (-...

background and aims. promoting remineralization is the ultimate goal of clinical prevention of caries lesion. the present in vitro study aimed to investigate the effect of grape seed extract (gse) on artificial enamel caries in primary human teeth. materials and methods. seventeen human sound primary incisors were sectioned mesiodistally. the tooth slices were placed in a demineralizing solutio...

thirty six wistar albino rats with implant induced endometriosis were randomly divided into six groups of six animals each. the rats in the first group received nothing and were euthanized at day 21. in the second group, rats received nothing and were euthanized at day 36. the third group received atorvastatin (atv; 5 mg kg-1 per day, orally) until 21 days from induction of endometriosis, and t...

BACKGROUND Diverse enzymatic and non-enzymatic antioxidants provide protection against reactive oxygen species in humans and other organisms. The nonenzymatic antioxidants include low molecular mass molecules such as plant-derived phenols. AIM OF STUDY This study identified the major phenolic compounds of a grape seed extract by HPLC and analyzed the effect of consumption of biscuits enriched...