نتایج جستجو برای: granulosa cel

تعداد نتایج: 7668  

2013
Helge Ræder Mette Vesterhus Abdelfattah El Ouaamari Joao A. Paulo Fiona E. McAllister Chong Wee Liew Jiang Hu Dan Kawamori Anders Molven Steven P. Gygi Pål R. Njølstad C. Ronald Kahn Rohit N. Kulkarni

BACKGROUND CEL-MODY is a monogenic form of diabetes with exocrine pancreatic insufficiency caused by mutations in CARBOXYL-ESTER LIPASE (CEL). The pathogenic processes underlying CEL-MODY are poorly understood, and the global knockout mouse model of the CEL gene (CELKO) did not recapitulate the disease. We therefore aimed to create and phenotype a mouse model specifically over-expressing mutate...

Journal: :iranian journal of basic medical sciences 0
sakineh kaboli kafshgiri department of biology, science and research branch, islamic azad university, tehran, iran kazem parivar department of biology, science and research branch, islamic azad university, tehran, iran javad baharara department of biology, research center for applied biology, mashhad branch, islamic azad university, mashhad, iran mohammad amin kerachian medical genetics research center, faculty of medicine, mashhad university of medical sciences, mashhad, iran department of medical genetics, faculty of medicine, mashhad university of medical sciences, mashhad, iran nasim hayati roodbari department of biology, science and research branch, islamic azad university, tehran, iran

objective(s): pesticides has wide range of infertility in female reproductive. this study was done to evaluate the effect of movento pesticide on development of granulosa cells and ovarian follicles and foxo1 and vnn1 gene expression in balb/c mice. materials and methods: in this study 40 healthy balb/c mice 5-6 weeks age were used. animals were randomly allocated into four groups. control (wit...

Journal: :CoRR 2017
Alejandro Grez Cristian Riveros Martín Ugarte Stijn Vansummeren

Complex Event Recognition (CER for short) refers to the activity of detecting patterns in streams of continuously arriving data. This field has been traditionally approached from a practical point of view, resulting in heterogeneous implementations with fundamentally different capabilities. The main reason behind this is that defining formal semantics for a CER language is not trivial: they usu...

Journal: :Biochimica et biophysica acta 2015
Hiromi Moriuchi Hideaki Unno Shuichiro Goda Hiroaki Tateno Jun Hirabayashi Tomomitsu Hatakeyama

BACKGROUND CEL-I is a galactose/N-acetylgalactosamine-specific C-type lectin isolated from the sea cucumber Cucumaria echinata. Its carbohydrate-binding site contains a QPD (Gln-Pro-Asp) motif, which is generally recognized as the galactose specificity-determining motif in the C-type lectins. In our previous study, replacement of the QPD motif by an EPN (Glu-Pro-Asn) motif led to a weak binding...

Journal: :The Journal of General Physiology 1955
J. H. Milstone

1. In batch adsorptions with prothrombin solutions, hyflo was the weakest adsorbent, standard super-cel intermediate, and filter-cel strongest. Of these three grades of diatomaceous earth, hyflo has the smallest surface area per gram and filter-cel the largest. In parallel breakthrough experiments, a column of standard super-cel had a capacity almost six times that of a hyflo column. 2. After p...

Journal: :Nucleic acids research 1998
C A Oleykowski C R Bronson Mullins A K Godwin A T Yeung

We have discovered a useful new reagent for mutation detection, a novel nuclease CEL I from celery. It is specific for DNA distortions and mismatches from pH 6 to 9. Incision is on the 3'-side of the mismatch site in one of the two DNA strands in a heteroduplex. CEL I-like nucleases are found in many plants. We report here that a simple method of enzyme mutation detection using CEL I can effici...

2017
Bin Li Guangsen Zhang Cui Li Ruijuan Li Jingchen Lu Zhengxi He Quan Wang Zhenzi Peng Jun Wang Yeping Dong Chunfang Zhang Jie Qiong Tan Nacef Bahri Yuexiang Wang Chaojun Duan

The Fip1-like1 (FIP1L1)-platelet-derived growth factor receptor alpha (PDGFRA) (F/P) oncogene can cause chronic eosinophilic leukemia (CEL), but requires IL-5 cytokine participation. In this study, we investigate the mechanism of F/P in collaboration with IL-5 in CEL. The results showed that Lyn, a key effector in the IL-5-motivated eosinophil production, is extensively activated in F/P-positiv...

Journal: :The Journal of biological chemistry 2004
Tatsuya Uchida Takayuki Yamasaki Seiichiro Eto Hajime Sugawara Genji Kurisu Atsushi Nakagawa Masami Kusunoki Tomomitsu Hatakeyama

CEL-III is a Ca(2+)-dependent and galactose-specific lectin purified from the sea cucumber, Cucumaria echinata, which exhibits hemolytic and hemagglutinating activities. Six molecules of CEL-III are assumed to oligomerize to form an ion-permeable pore in the cell membrane. We have determined the crystal structure of CELIII by using single isomorphous replacement aided by anomalous scattering in...

2013
George L.J. Hull Jayne V. Woodside Jennifer M. Ames Geraldine J. Cuskelly

Epidemiological studies show that elevated plasma levels of advanced glycation end products (AGEs) are associated with diabetes, kidney disease, and heart disease. Thus AGEs have been used as disease progression markers. However, the effects of variations in biological sample processing procedures on the level of AGEs in plasma/serum samples have not been investigated. The objective of this inv...

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