نتایج جستجو برای: granulocytes

تعداد نتایج: 5616  

Journal: :Micron 2016
Brian M Preziosi Timothy J Bowden

The Atlantic jackknife clam, Ensis directus, is currently being researched as a potential species for aquaculture operations in Maine. The goal of this study was to describe the hemocytes of this species for the first time and provide a morphological classification scheme. We viewed hemocytes under light microscopy (using Hemacolor, neutral red, and Pappenheim's stains) as well as transmission ...

Journal: :Journal of immunology 2006
Tomokazu Ohnishi Kyoko Kakimoto Kenjiro Bandow Charles J Lowenstein Yasushi Daikuhara Tetsuya Matsuguchi

Serum hepatocyte growth factor (HGF) is rapidly increased in patients suffering from various tissue injuries including arterial occlusive diseases. However, the cellular sources of the HGF increase remain largely unknown. In the present study, we showed that bioactive mature HGF is constitutively present on the surface of granulocytes in human peripheral blood. Exogenously added 125I-labeled io...

Journal: :Haematologica 2008
Agata Drewniak Jaap-Jan Boelens Hans Vrielink Anton T J Tool Marrie C A Bruin Marry van den Heuvel-Eibrink Lynne Ball Marianne D van de Wetering Dirk Roos Taco W Kuijpers

BACKGROUND Granulocyte transfusion has been proposed as a bridging therapy for patients with prolonged periods of chemotherapy-induced neutropenia, who suffer from severe fungal and bacterial infections. To recover, adequate numbers of granulocytes are required when the patients are refractory to standard treatment. The aim of this study was to assess the functional characteristics and efficacy...

Journal: :American Journal of Clinical Pathology 2007

Journal: :Journal of Experimental Medicine 1976

2013
LAKSHMI KANNAN MARY FRANCES MCMULLIN PAUL WINTER

Objective: A pilot study to test the hypothesis that dysregulated expression of haemostasis genes in clonal granulocytes of MPD patients contributes to the genesis of haemostatic complications. In this study of 36 patients with MPD and 18 healthy controls, specific target genes Procoagulant Tissue Factor [TF], prothrombotic cytokines Interlukin1 β [IL1β],Tumor Necrosis Factor α [TNFα],Vascular ...

Journal: :The Journal of Experimental Medicine 1978
S J Weiss P K Rustagi A F LoBuglio

Human granulocytes were capable of oxidizing 2-keto-4 thiomethylbutyric acid to ethylene during phagocytosis or membrane perturbation. The reaction required hydrogen peroxide and superoxide and in addition was inhibited by various hydroxyl radical (OH) scavengers. These observations represent direct evidence for the generation of OH by human granulocytes. Further, inhibition of ethylene generat...

Journal: :Folia biologica 2017
K Smetana D Mikulenková H Klamová

Granulocytic early progenitors and terminally differentiated - mature granulocytes with segmented nuclei were studied using computer-assisted diameter and heterochromatin optical image densitometry to provide more information on the nuclear size and heterochromatin condensation state. Bone marrow smears of patients suffering from chronic myeloid leukaemia untreated as well as treated with "spec...

Journal: :Blood 2010
Agata Drewniak Anton T J Tool Judy Geissler Robin van Bruggen Timo K van den Berg Taco W Kuijpers

Transfusion of granulocytes from granulocyte-colony stimulating factor (G-CSF)/dexamethasone (dexa)-treated donors can be beneficial for neutropenic recipients that are refractory to antimicrobial therapy. G-CSF/dexa treatment not only increases the number of circulating neutrophils but also affects their gene expression. Because of the intended transfusion of these granulocytes into patients w...

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