A unique, sensitive, and highly specific immunoassay system for antibodies using gold nanoparticles has been developed. The assay is based on the aggregation of gold nanoparticles that are coated with protein antigens in the presence of their corresponding antibodies. The aggregation of the gold nanoparticles results in an absorption change at 620 nm that is monitored using an absorption plate ...

The anodic stripping voltammetric determination of gold was accomplished on a chemically modified glassy carbon electrode in a solution containing chloride ions. A modifying polymer, polyvinylferrocene, was coated by immersing the glassy carbon surface in its solution in methylene chloride followed by solvent evaporation. Tetrahalo complexes of gold, tetrachloroaurate(III) and tetrabromoaurate(...

BACKGROUND The impact of gold nanoparticles on cell viability has been extensively studied in the past. Size, shape and surface functionalization including opsonization of gold particles ranging from a few nanometers to hundreds of nanometers are among the most crucial parameters that have been focussed on. Cytoxicity of nanomaterial has been assessed by common cytotoxicity assays targeting enz...

alpha 2-Macroglobulin (alpha 2 M) was adsorbed to colloidal gold and used as a new tool in the study of receptor-mediated endocytosis. alpha 2 M-gold is easy to prepare and is clearly visualized at the electron microscope level. When cells were incubated with alpha 2 M-gold at 0 degrees C, gold was visualized both diffusely over the cell surface and concentrated in coated pits. After cells to w...

Polyelectrolyte surface-modified cowpea mosaic virus (CPMV) can be used for the templated synthesis of narrowly dispersed gold nanoparticles. Cationic polyelectrolyte, poly(allylamine) hydrochloride, is electrostatically bound to the external surface of the virus capsid. The polyelectrolyte-coated CPMV promotes adsorption of aqueous gold hydroxide anionic species, prepared from gold(III) chlori...

in this article electrochemical determination of captopril at the surface of the platinum coated nanoporous gold film (ptnpgf) electrode is reported using the cyclic voltammetry and amperometry. for the preparation of ptnpgf, the surface of npgf electrode was covered with cu layer using underpotential electrochemical deposition (upd).afterward, the copper layer is replaced with platinum ions vi...