To explore further the relation between admission glucose concentration and outcome in stroke, we measured glucose, fructosamine, and glycosylated hemoglobin concentrations on admission in 216 patients seen within 24 hours after the onset of their first stroke. Fructosamine concentration reflects the degree of glycemia in the preceding 4-6 weeks and glycosylated hemoglobin concentration reflect...

The anode Is at the left, the origin at the rlt. Above Is a control consIstIng of HbA, F. S. and A2.Below Is the concentrated column eluate. Note the fast hemoglobIn band at the far left and carbonIc anhy-&ase B near the origIn atthe rIght In the pattern for the column eluate 1250 CLINICAL CHEMISTRY. dure is applicable also to other situations , e.g.,to the measurements of specific radioactivit...

We have devised a rapid and convenient method of eliminating the contribution of labile glycosylated hemoglobin in the hemoglobin A1 assay. The procedure requires a 30-min incubation of erythrocytes in 30 mM semicarbazide and 12 mM aniline (pH 5, 38 degrees C). This chemical means of eliminating the labile fraction is as effective as a 14-h incubation in isotonic saline as measured with high-pr...

Introduction: Iron deficiency anemia (IDA) has been shown to cause a false increase in glycosylated hemoglobin (HBA1c), but how much (Hgb) causes certain decrease HBA1c remains unknown. Knowledge of this ratio will enable more accurate clinical diagnosis and follow-up diabetes. This study aimed investigate whether IDA if it does, causes. 
 Material Method: One hundred twenty-two patients w...

BACKGROUND Vildagliptin is a dipeptidyl peptidase IV inhibitor (DPP4i). Its efficacy and safety of DPP4i in Chilean real life type 2 diabetic (T2D) patients is not well known. AIM To assess the safety profile and effectiveness of 12 weeks of treatment with Vildagliptin for glycemic control in T2D Chilean patients with a poor glycemic control. PATIENTS AND METHODS Retrospective assessment of...

Retrospective analysis of glycosylated haemoglobin concentrations in a diabetic outpatient clinic over three and a half years showed a small seasonal variation in the mean value with a peak in mid February and a nadir in mid August.

AIMS To provide evidence on the comparative effectiveness of oral diabetes drug combinations. METHODS We performed a retrospective, observational cohort study of glycosylated hemoglobin change in outpatients newly exposed to dual- or triple-drug oral diabetes treatment. RESULTS Adjusted response to a second drug added to metformin ranged from 0.85 to 1.21% glycosylated hemoglobin decline. R...