Lung Cancer Metabolic reprogramming is a hallmark of metastatic lung cancer cells (A549_3R). In article number 2200050, Victor Shahin and co-workers establish that 5-7 carbon glycols reduce the A549_3R ATP production by interfering with LDH mitochondria. The cover image reveals decline in mitochondrial membrane potential when exposed to 1,6-HD.

Formation of organogels from covalently linked polyethylene glycols and cyclodextrins and their encapsulation/release properties were monitored with EPR spectroscopy using spin labels and spin probes; changes in molecular tumbling rates provided information on spin probe/label location inside the gel network, and molecular properties of the gel.