BACKGROUND Based upon the acquainted loss of dopaminergic neurons in the substantia nigra in Parkinson's disease (PD), we hypothesised changes in magnetic resonance imaging signal intensities of the basal ganglia to be useful as an additional technical tool in the diagnostic work-up. METHODS Region-of-interest analyses (substantia nigra and globus pallidus internus) of T2-weighted scans were ...

An image of increased signal intensity on T2-weighted images in the central area globus pallidus (caused by necrosis and edema) surrounded a zone reduced (representing iron deposits) brain magnetic resonance is called eye tiger sign.

BACKGROUND AND PURPOSE Globus sensation is common and difficult to treat. The purpose of our study was to compare the diagnostic and therapeutic efficacy of barium esophagram and neck CT in patients with isolated globus sensation, to determine which of these modalities should be preferred in the evaluation of this condition. MATERIALS AND METHODS We retrospectively identified patients present...

INTRODUCTION The globus sensation is a constant feeling of a lump in the throat and may be associated with thyroid enlargement. A two year prospective study was set up to ascertain the relationship between thyroid pathology and globus symptoms. MATERIALS AND METHODS All patients undergoing thyroid surgery over a two year period were included. Patients were questioned pre- and post-operatively...

The anatomical organization and electrophysiological characteristics of a projection from the nucleus accumbens to anteroventral parts of the globus pallidus and to a subpallidal region that includes the substantia innominata (SI), the lateral preoptic area (LPO), and anterior parts of the lateral hypothalamic area (LHA) were investigated in the rat. Autoradiographic experiments, with injection...

The benefits offered by the Grid architecture has resulted in the tremendous growth of the Grid-user community. The Globus Toolkit has emerged as the most popular Grid implementation used by the Grid community. The Java CoG Kit provides a rich suite of artifacts and client-side constructs for Globus Toolkit 2 and 3 to access the backend Globus enabled Grid functionality. This paper is motivated...

Histological, behavioral and electrophysiological studies have suggested that 5-HT may regulate motor function by affecting globus pallidus neurons activity. In this study, the effects of 5-HT in globus pallidus on haloperidol-induced catalepsy and its possible receptor mechanisms were examined in rats using bar tests. Bilateral microinjection of 5-HT (10microM) into globus pallidus significant...

Objective To examine whether pharyngeal swallowing function is impaired in globus patients with swallowing difficulty by dynamic swallowing study. Methods Dynamic swallowing studies were performed on 80 normal adult volunteers and 33 globus patients with swallowing difficulty. Objective parameters such as maximum displacement of the hyoid bone, pharyngeal transit time, pharyngeal constriction...

BACKGROUND AND PURPOSE Gadolinium-based contrast agents have been associated with lasting high T1-weighted signal intensity in the dentate nucleus and globus pallidus, with histopathologically confirmed gadolinium retention. We aimed to longitudinally investigate the relationship of multiple gadolinium-based contrast agent administrations to the Signal Intensity Index in the dentate nucleus and...