Glanzmann thrombasthenia is an inherited bleeding disorder due to a functional reduction or absence of platelet GPIIb/IIIa (alphaIIbbeta3) integrin receptors. Based on a prolonged bleeding time and absence of platelet aggregation in response to physiologic agonists, a 55-year-old white man was diagnosed as having Glanzmann thrombasthenia. The patient's platelet fibrinogen level was approximatel...

The tutorial between GP Trainer and GP Registrar is at the centre of learning and assessment in General Practice. However, the content and style of the tutorial is left to the discretion of the trainer themselves and the evaluation of this tutorial is carried out in an unsystematic way. Therefore, the present study aimed to explore what GPs believe constitutes a good tutorial in terms of the be...

Platelets play a critical role in hemostasis and are involved in wound repair and inflammatory processes. Contact to the subendothelial matrix induces platelet activation that is followed by release of cytokines and growth factors and formation of a vascular plug. Several inherited defects of platelet function resulting in bleeding diathesis are known. However, only in the minority of these dis...

Glanzmann thrombastenia (GT) is a rare condition of an inherited autosomal recessive gene characterized with bleeding tendency. The condition is rarely met in the OR. and therefore it is essential that anesthesiologist be cognizant of the risk involved and be prepared with all necessary precautionary measures. We present a GT case in a 27-year-old male with a mass in the anticubital region of r...