Ginkgo biloba is the most popular phytotherapic agent used worldwide for treatment of several human disorders. However, the mechanisms involved in the protective actions of Ginkgo biloba on cardiovascular diseases remain poorly elucidated. Taking into account recent studies showing beneficial actions of cholinergic signaling in the heart and the cholinergic hypothesis of Ginkgo biloba-mediated ...

BACKGROUND The benefit of Ginkgo biloba for the treatment of dementia remains controversial. The aim of this study was to evaluate the efficacy and safety of Ginkgo biloba in patients with dementia in whom administration effects were reported using meta-analysis. METHODS We searched MEDLINE, Embase, the Cochrane databases, and Ichushi for controlled trials of Ginkgo biloba for the treatment d...

BACKGROUND There is some evidence to suggest that ginseng and Ginkgo biloba can improve cognitive performance, however, very little is known about the mechanisms associated with such improvement. Here, we tested whether cardiovascular reactivity to a task is associated with cognitive improvement. METHODOLOGY/PRINCIPAL FINDINGS Using a double-blind, placebo controlled, crossover design, partic...

Protracted periods of increased cortisol production, as may be seen in an acute illness, may lead to transient hyperglycemia. Increasing evidence suggests that cortisol may then mediate the development of insulin resistance and potentially lead to the development of overt diabetes. Evidence in animal studies also suggests that under conditions of stress Ginkgo biloba extract could reduce plasma...

urease enzyme has a crucial role in the persistent habitation of helicobacter pylori (h. pylori) that induces gastrointestinal diseases, in particular gastritis, duodenal, peptic ulcer, and gastric cancer. plants have long been utilized as the biggest source of substances with medicinal properties from natural origin and therefore result in less toxicity and adverse side effects upon usage. 15 ...

the antioxidant activity of the different extracts and fractions of aerial parts of otostegia persica (burm.) boiss. were evaluated using beta-carotene bleaching and lipid peroxidation methods. the inhibitory activity of the plant extracts on the peroxidation of linoleic acid were measured by ferric thiocyanate method in comparison to methanolic extracts of green tee, ginkgo biloba, vit.e and b...

OBJECTIVES Doubt over the cost-effectiveness of the cholinesterase inhibitors in dementia has renewed interest in alternative treatments such as Ginkgo biloba. We aimed to determine the effectiveness and the safety profile of Ginkgo biloba for treating early stage dementia in a community setting. METHODS We conducted a community-based, pragmatic, randomised, double-blind, parallel-group trial...

Objectives/Goals Pharmaceutical companies have marketed Ginkgo biloba leaf extracts as a memory and concentration enhancer as well as a treatment for Alzheimer's disease and dementia patients. However, there have been numerous studies with varying results about the benefits of G. biloba. My objective was to determine whether G. biloba affects synaptic plasticity via cytoskeletal protein concent...

BACKGROUND Ginkgo Bilboa injection has had been clinically applied to restore the damaged cells and tissues due to the ischemia through improving the cerebral blood supply and decreasing the oxygen consumption. OBJECTIVE/AIM To evaluate the Ginkgo Bilboa injection's therapeutic role towards ischemia/ reperfusion (I/R) injury through determination of monoamine neurotransmitter dopamine (DA) in...