BACKGROUND Inflammatory gingival enlargement is a common observation in routine dental practice. Drugs like nifedipine, used for hypertension and Porphyromonas gingivalis infection-induced gingival enlargement is of a major concern. The current study aims to identify the inflammatory response of the gingival enlargement by measuring the major inflammatory markers fibrinogen and C-reactive prote...

Introduction: Gingival inflammation often persists despite conventional therapies. A topical gingival patch containing natural extracts has been shown in a randomized clinical trial to reduce gingival inflammation when administered as an independent therapy. We report a case series of patients with moderate-to-severe chronic periodontitis in whom the patch was used together with scaling and roo...

objectives: the present study was conducted to determine the effect of local and systemic inflammation on the quantity and localisation of gingival mesenchymal stem cells (gmscs). materials & methods: gingival samples were collected from 34 systemically healthy (group1) and 10 consenting adult patients with type 2 diabetes mellitus (t2dm) (group2) who had reported for various dental treatment r...

OBJECTIVE To assess the changes in the level of C-reactive protein (CRP) and tumor necrosis factor-alpha (TNF-alpha) in gingival crevicular fluid (GCF) after treatment of chronic gingivitis in systemically healthy individuals. METHODS This is a clinical trial conducted at Case Western Reserve University, Cleveland, Ohio, United States of America from February to December 2011. A total of 41 s...

Gingivitis is an inflammatory disease that affects gingival tissues through a microbe-immune interaction. Huanglian Jiedu decoction (HLJD) is used traditionally for clearing and detoxifying in China, which had been reported to possess many pharmacological effects. Rat gingival inflammation model was established by lipopolysaccharide (LPS) injection for 3 consecutive days, and HLJD was given by ...

Objective: To evaluate the relationship of phenytoin-induced gingival enlargement and inflammation to find out if there is any significant correlation between hyperplastic index and periodontal parameters, the number of fibroblasts and phagocytic cells. Background: The introduction of phenytoin as an anti-epileptic drug in 1938 marked the beginning of a new era in the treatment of grandmal epil...

BACKGROUND The aim of this study was to determine the presence of matrix metalloproteinase-8 in the gingival crevicular fluid (GCF) of patients after acute myocardial infarction (AMI). METHODS A total of 48 GCF samples from 20 AMI patients, hospitalized at the Department of Cardiology and Angiology of the Johannes Gutenberg University Mainz, were investigated. Besides the myocardial infarctio...

OBJECTIVE The aim of this retrospective study was to evaluate the relationship between orthodontic treatment and gingival health. MATERIALS AND METHODS A total of 251 patients among whom 177 were girls and 74 were boys, recruited from the records pool of the Department of Orthodontics, Faculty of Dentistry, University of Gazi, were included in the study. Patients' treatments have been complet...

BACKGROUND Power-driven toothbrushes (PDT) have been designed to improve the efficacy of oral hygiene. It is not clear how they compare in efficacy with manual toothbrushes in cause-related periodontal therapy. OBJECTIVES To evaluate the effectiveness of the use of a PDT as compared with a manual toothbrush (MT), in terms of gingival bleeding or inflammation resolution, in cause-related perio...