background: among the most important parasitic disease, causing diarrhea, gi­ardia lamblia is noteworthy. nowadays detection methods for these parasites in­clude parasitological methods such as microscopic examination. the sensitivity of these methods relies on the expertise and experience of examiners. in contrast, molecular methods such as pcr are less dependent on the expertise of the exam­i...

background: giardia has the ability to infect many mammals including dogs, cats, deer, mice, ground squirrels, chinchillas, swine, rabbits, pocket mice, oxen, guinea pigs, and humans. giardia lamblia (also giardia duodenalis, g.intestinalis) isolates have been variably divided into two or three genotypes by different investigators, and each group can be divided into subgroups. objectives: we ha...

in an antigenic variant. Giardia lamblia: loss of the CRP170 gene The cysteine-rich protein gene family of

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Giardia infection is one of the most common causes of waterborne diarrheal disease in a wide array of mammalian hosts, including humans globally. Although numerous studies have indicated that adaptive immune responses are important for Giardia defense, however, whether the host innate immune system such as TLRs recognizes Giardia remains poorly understood. TLR2 plays a crucial role in pathogen ...

INDIAN PEDIATRICS 1161 VOLUME 42__NOVEMBER 17, 2005 Nitazoxanide (NTZ) is a novel broadspectrum antiparasitic agent originally discovered in 1980s by J.F. Rossignol. Nitazoxanide is effective in broad range of parasitic and protozoal infections including Giardia lamblia, Entamoeba histolytica, Cryptosporidium spp., Ascaris lumbricoides, Hymenolepis nana and Taenia solium/saginata. In combinatio...

The competitive interactions of genetically distinct isolates of Giardia duodenalis with different growth rates were studied in vitro. Electrophoretic analysis of mixed cultures showed that competition between 2 cloned isolates occurs under normal in vitro culture conditions, with faster-growing isolates outcompeting those with slower growth rates. The addition of sublethal concentrations of me...

AIM To compare the use of commercial monoclonal antibody test systems--the Giardia CEL IF test and the Crypto CEL IF test--for the detection of Giardia lamblia and Cryptosporidium parvum antigens in faeces with conventional techniques. METHODS Sensitivity and specificity were evaluated using preparations of cysts of G lamblia and purified oocysts of C parvum. Evaluation of 59 random faecal sa...