Giant cells are the soldiers of defensive system of our body. They differ based on the stimuli that provoked their formation. On the other hand, squamous cell carcinoma (SCC) being the most common oral cancer, presents with varied histopathological features based on the degree of differentiation. Keratinizing islands of dysplastic squamous epithelial cells & a dense inflammatory response form t...

introduction: central giant cell granuloma is a benign lesion but sometimes has aggressive proliferation composed of multinucleated giant cells in a background of spindle and ovoid mesenchymal cells. multifocal central giant cell granuloma of jaws is very rare and usually associated with hyperparathyroidism and some syndromes. we described an un-usual case of a 22-year-old man with idi-opathic ...

central giant cell granuloma is a benign, aggressive neoplasm composed of multinucleated giant cells that almost exclusively occurs in the jaws though extra-gnathic incidence is rare.multifocal cgcgs of the jaws are very rare and suggestive of systemic diseases such as hyperparathyroidism,an inherited syndrome such as noonan-like multiple giant cell lesion syndrome or other disorders.very few c...

Abstract Background A case of simultaneous adrenocortical and renal cell carcinoma due to long-term lead exposure from residual gun pellets is a rare relatively unknown topic in the literature. Case presentation We present 43-year-old male patient with giant retroperitoneal tumor. Thirteen years before he had shotgun injury left upper side abdomen are abdominal wall. Extirpation tumor kidney wa...

Giant cell carcinoma of the lung is an unusual form of pulmonary malignancy that follows an extremely aggressive clinical course. We report the clinical and roentgenographic manifestations of 14 patients with pathologically proven giant cell carcinoma of the lung, and compare our data to other reports in the literature. Our patients often presented with or developed constitutional or nonthoraci...

Cervical carcinoma is the most common malignancy of the female genital tract and represents the second most common malignancy in women worldwide. Histologically 85 to 90% of cervical cancers are squamous cell carcinoma. Osteoclastic giant cell rich squamous cell carcinoma is an unusual histological variant of which only 4 cases have been reported. We present the case of a 49-year-old woman with...

metastatic lesions represent 1-8% of all malignant tumors of the mouth and jaws, which are regarded as rare sites of metastases from different primary tumors. metastases in mouth soft tissue are also rare, and within these it is on the gums where they more frequently occur. primary tumors which metastasize to the mouth are most commonly: lung, breast, and kidney. clear cell carcinoma is the mos...

Less than 1% of basal cell carcinomas are giant basal cell carcinomas. Giant basal cell carcinomas are rare. They preferentially involve the trunk and are commonly associated with neglect. Giant basal cell carcinomas of 10 cm or greater are associated with a high rate of metastasis. We report a case of giant basal cell carcinoma of the leg which is not associated with neglect and no signs of me...

Abstract Basal cell carcinoma (BCC) is the most common skin cancer. However, BCC on scrotum very rare, with an incidence of 0.03%. Giant BCC, in which tumour larger than 5 cm, has also been reported as a rare variant. Here, we report 71‐year‐old male giant and review similar cases English. None four scrotum, including present case, showed lymph node or distant metastasis. Wide local excision wa...