The Gestational Trophoblastic Disease includes an interrelated group of diseases originating from placental tissue, with distinct behaviors concerning local invasion and metastasis. The high sensitivity of the serial dosages of human chorionic gonadotrophin, combined with advances in chemotherapy treatment, have made gestational trophoblastic neoplasia curable, most often through chemotherapy. ...

gestational trophoblastic neoplasia ( gtn) is one of the most common gynecologic tumors in our country. despite development of effective chemotherapy: some cases remain resistant and if there is only focus of tumor, resection would be indicated.we present a young woman with stage 1 persistant gtn showing no response to chemotherapy. transvaginal sonograpy revealed trophoblastic tissue in the ut...

OBJECTIVE To evaluate the role of surgery in the management of high-risk gestational trophoblastic neoplasia. STUDY DESIGN Twenty-four (48%) of 50 patients treated with etoposide, methotrexate, actinomycin D, cyclophosphamide and vincristine (EMA-CO) regimen as primary or secondary chemotherapy for high-risk gestational trophoblastic neoplasia between 1986 and 2005 underwent 28 adjuvant surgi...

Gestational trophoblastic disease (MTG) groups together conditions that are very variable from a clinical, biological and metastatic potential point of view.We report case ruptured molar pregnancy, diagnosed by picture hemorrhagic shock, confirmed histological examination the surgical specimen. Monitoring was assaying plasma BhCG levels.

Various forms of trophoblastic diseases were reported in the literature, including complete and partial hydatidiform moles, gestational choriocarcinomas, placental-site epitheloid tumors. Among patients who suffer from mole, neoplasia can be easily diagnosed by using levels human chorionic gonadotropin (hCG). Therefore, complex investigations are not usually necessary measuring hCG, physical ex...