Gestational hypothyroidism is a prevalent disorder in pregnant women. We aimed to investigate the impact of experimental gestational hypothyroidism (EGH) on cardiovascular and autonomic nervous systems (ANS) in the offspring of rats. EGH was induced with methimazole (MMI) 0.02% in drinking water from day 9 of gestation until birth. Sixty day old offspring from MMI-treated dams (OMTD, n=13) or w...

Introduction: Small for gestational age (SGA) refers to birth weight of neonates less than 10th percentile or 2nd standard deviation below the population norms on growth charts.
 Aims: To identify common risk factors and morbidities small babies.
 Methods: This is a cross sectional descriptive study it has been conducted at Department pediatrics, Nepalgunj Medical college which tertia...

Thyroxine (T4) screening values in infants of low birthweight in relation to birthweight and gestational age are reported. There were 86 healthy infants of low birthweight (group 1), and 29 preterm infants with respiratory distress syndrome (group 2). All the group 2 infants and 36% of those in group 1 had a T4 screening value below the cut-off point (-2.1 SD). In group 1 there was a significan...

Maternal hypothyroidism has previously been shown to increase risk for neonatal intensive care treatment, but otherwise the association between thyroid diseases and neonatal morbidity is understudied. The Consortium on Safe Labor, a retrospective cohort (2002-2008), included 223,512 singleton deliveries of which 0.2% had hyperthyroidism, 1.4% primary and 0.1% iatrogenic hypothyroidism, and 1.3%...

Aim: The aim of the study is to determine frequency first-trimester thyroid dysfunction in pregnant women and investigate effect on some perinatal outcomes.
 Material Method: In study, Thyroid stimulating hormone (TSH), free T4 T3 values who applied our outpatient clinic were retrospectively scanned recorded. As a result, 3224 included study. Pregnant evaluated as overt hypothyroidism, sub...

Background: Thyroid disorders have a yet unclear impact on obstetric complications. The studies been varied and mostly contradictory. aim of the study was to examine pattern thyroid its Methods: This cross-sectional enrolled 334 pregnant women less than 12 weeks gestation. After routine clinical ultrasound evaluation all cases, baseline investigations TSH done. In cases with low free T3 T4 All ...

1 Thyroid hormones (THs) are essential for proper brain development in mammals. TH insufficiency 2 during early development causes structural and functional abnormalities in brain leading to cognitive 3 dysfunction. The specific effects of developmental hypothyroidism on attention have not been well 4 characterized in animal models. The present study was conducted to characterize the effects of...