intraventricular hemorrhage (ivh) is an important cause of brain injury in premature neonates. current study tries to define associated risk factors of ivh in preterm neonates in aliasghar children hospital during 2008 to 2011. in this study, the risk factors have been evaluated in premature neonates with ivh, who had at least one brain sonography since their admission in nicu. a total of 63 pr...

Purpose. Primary hemorrhage in the ventricular system without a recognizable parenchymal component is very rare. This single-center retrospective study aimed to further characterize the clinical characteristics and early outcome of this stroke subtype. Methods. All patients with primary intraventricular hemorrhage included in a prospective hospital-based stroke registry over a 19-year period we...

CONTEXT Infants born prematurely are at risk for a perinatal encephalopathy characterized by white and gray matter injuries that affect subsequent cortical development and neural connectivity and potentially increase risk for later psychiatric disorder. OBJECTIVE To determine the relation of perinatal brain injury, as detected by neonatal head ultrasound, to psychiatric disorders in adolescen...

PURPOSE To examine the vascular supply and architecture of the germinal matrix in the preterm neonatal brain and to determine whether veins or arterioles are the source of germinal matrix hemorrhage. METHODS Brains from eight preterm neonates (24 to 35 weeks' gestation) and two full-term infants were fixed in alcohol, embedded in celloidin, sectioned at 100- and 500-micron thicknesses, staine...

OBJECTIVES We tested the hypothesis that administration of magnesium sulfate in labor protects against the development of neonatal brain lesions and cerebral palsy (CP) in low birth weight infants. METHODS Magnesium exposure was ascertained in a population-based cohort of 1105 infants weighing 2000 g or less through review of medical records of maternal magnesium sulfate administration and, w...

The main neonatal stroke syndromes discussed in this article are: arterial ischemic stroke (AIS), including perinatal AIS, and "presumed" perinatal AIS; cerebral venous thrombosis, including cortical vein and venous sinus thrombosis and germinal matrix hemorrhage/periventricular hemorrhagic infarction; and intraparenchymal hemorrhage. This review discusses general pathophysiological mechanisms ...

conclusions intraventricular hemorrhage followed by comatose state is a rare finding of the castor bean seed ingestion. the patient’s condition improved dramatically after ffp transfusion. introduction castor bean seed is used to control some medical conditions including diabetes mellitus due to popular belief in its effectiveness. however it may cause severe poisoning in humans and animals and...

Periventricular/intraventricular hemorrhage (PVH/IVH) into brain can occur in premature infants and is associated with poor developmental outcome. The purpose of this study was to develop and characterize a model of PVH/IVH in newborn mouse. We hypothesized that periventricular germinal matrix would exhibit reduced cell proliferation. PVH/IVH was induced in 1-day-old mice by injection of autolo...