Background and aim : Genital wart is a common sexually transmitted disease caused by different types of human papilloma virus (HPV). Cryotherapy is one of the most commonly used treatment options. Trichloroacetic acid (TCA) is another therapy commonly used in treatment of genital warts.Materials and methods: The objective of his study was to evaluate and compare the efficacy and adverse effects...

Imiquimod (IQ) has been successfully used in treatment of genital warts. In clinical settings, patients responded well but wart reduction rates varied. Our aim was to find a correlation between clinical responses and pretreatment (constitutive) levels of genes that might be involved in the molecular action of IQ. Since IQ is a cytokine inducer, we analyzed levels of expression of genes of the J...

WHILE the pathology and virology of human skin warts have received considerable attention in the last few years, little work has been done to establish the relationship of genital warts to warts in general, or even to establish if these lesions are of viral origin. The viral aetiology of the human skin wart (verruca vulgaris, plana, and plantaris) is now well established. By use of the electron...

Objective To review published randomised controlled trials to assess the benefit and harm of imiquimod in the treatment of external genital warts. Data sources MEDLINE (1966 – December 2000), Cochrane Library (Issue 3, 2000) and PubMed (December 15, 2000), review articles and reference lists. Review methods Included studies had to be randomised trials of imiquimod, to be full published papers, ...

OBJECTIVE To review published randomised controlled trials to assess the benefit and harm of imiquimod in the treatment of external genital warts. DATA SOURCES MEDLINE (1966 - December 2000), Cochrane Library (Issue 3, 2000) and PubMed (December 15, 2000), review articles and reference lists. REVIEW METHODS Included studies had to be randomised trials of imiquimod, to be full published pape...

Thirty-nine patients with condylomas (12 women and 27 men) attending a dermatology clinic were tested for genital human papillomavirus (HPV) DNA and for seroprevalence to HPV type 6 (HPV6) L1 virus-like particles. The L1 consensus PCR system (with primers MY09 and MY11) was used to determine the presence and types of HPV in sample specimens. All 37 (100%) patients with sufficient DNA specimens ...

Anogenital warts represent a major therapeutic problem in genitourinary medicine. A wide range of treatment modalities is available (the usual indication that none is ideal). This therapeutic problem is not new; in the sixth century, Dionysius graphically described treatment of genital warts: "The surgeons spared neither iron nor fire, and were not moved to pity by the cries of the patients". B...

HPV-associated diseases, such as cervical and other anogenital cancers, cervical and anal intraepithelial neoplasia, genital warts, and recurrent respiratory papillomatosis confer considerable morbidity and mortality, and are significant health care concerns. Successful vaccination strategies that protect against HPV infection are expected to substantially reduce HPV-related disease burden. Pro...

The human papillomavirus is a DNA virus that is involved in the pathogenesis of several benign and malignant lesions. Although numerous types of HPV exist, vaccines currently target HPV’s 6, 11, 16, and 18, which are the most commonly implicated in verrucae and oral-genital neoplasms. Although the HPV vaccine has been recommended as part of the vaccination schedule in adolescents for several ye...