Deleterious genetic variants can be evaluated as quantitative traits using information theory-based sequence analysis of recognition sites. To assess the effect of such variants, fitness and genetic load of SNPs which alter binding site affinity are derived from changes in individual information and allele frequencies. Human SNPs that alter mRNA splicing are partitioned according to their genet...

DNA barcoding is a simple method for the identification of any species using a short genetic sequence from a standard genome section. The present study aimed at examining the nuclear and chloroplast diversity as well as the phylogenetic relationships of eight species of saffron including four spring-flowering and five autumn-flowering species from different parts of Iran, using the nuclear barc...

In an ongoing research, 24 cultivated and wild cultivars of barley were evaluated for morphological characteristics of grain, pollen, and stomata. Traits of interest included length, width, and area. Results of variance analysis showed that all samples were differed in traits of stomata, grain, and pollen at probability levels of 1 and 5%, suggesting remarkable genetic variation among studied s...

We found significant sex differences in the mtDNA genetic structure and dispersal patterns of great bustards in a population of 11 breeding groups, "leks", in central Spain. The analysis of genetic distances showed that the female population was divided into three groups of leks separated by ca. 50 km, whereas male haplotypes were randomly distributed among leks. Genetic distances among pairs o...

Capparis spinosa L. (Capparidaceae) is the largest genus of family Capparaceae, distributed in pantropical region. C. known as a medicinal plant species. In Iran, different parts caper bush plants are used diuretics, tonics and treatment malaria joint disease. Till present time, there has been no detailed information available on molecular phylogeny genetic structure these species country. Ther...

TCR reactivity is tuned during thymic development. Immature thymocytes respond to low-affinity self-ligands resulting in positive selection. Following differentiation, T cells no longer respond to low-affinity ligands, but respond well to high-affinity (foreign) ligands. We show in this study that this response includes integrin activation, supramolecular activation cluster formation, Ca(2+) fl...

Genetic sequences of a highly pathogenic avian influenza (H5N8) virus in England have high homology to those detected in mainland Europe and Asia during 2014. Genetic characterization suggests this virus is an avian-adapted virus without specific affinity for zoonoses. Spatio-temporal detections of H5N8 imply a role for wild birds in virus spread.