Synthetic cannabinoid drugs do not cross react on traditional marijuana immunoassay tests, preventing their use in large scale drug screening programs. This paper describes the validation and performance characteristics of two enzyme linked immunosorbent assays designed to detect the use of two common synthetic cannabinoids in urine, JWH-018 and JWH-250. The JWH-018 assay has significant cross-...

In this paper, a trust region method for generalized semi-infinite programming problems is presented. The method is based on [O. Yi-gui, “A filter trust region method for solving semi-infinite programming problems”, J. Appl. Math. Comput. 29, 311 (2009)]. We transformed the method from standard to generalized semi-infinite programming problems. The semismooth reformulation of the Karush–Kuhn–Tu...

Bosnia and Herzegovina has experienced a turbulent post-independence transition. It can be argued that the level of trust is likely to have been negatively affected by this turbulence and that it is important to restore trust to achieve sustainable political and economic development. This paper looks at trust in Bosnia and Herzegovina and puts a special focus on the role of ethnicity. We find g...

Previous research has indicated that socio-economic and racial characteristics of an individual’s environment influence not only group consciousness and solidarity, but also affect his or her views toward minority or majority groups. Missing from this research is a consideration of how context, social interaction, and interracial experiences combine to shape more general psychological orientati...

We propose an opinion dynamics model that combines processes of vanity and opinion propagation. The interactions take place between randomly chosen pairs. During an interaction, the agents propagate their opinions about themselves and about other people they know. Moreover, each individual is subject to vanity: if her interlocutor seems to value her highly, then she increases her opinion about ...

The majority of existing trust models is based on three underlying assumptions: (i) proven identity of agents, (ii) repetitive interactions and (iii) similar trusting situations. In our work, we address these assumptions by introduction of simple classification techniques in our mechanism that extends existing trust models, rather than by introduction of a new model. The proposed approach forma...

Synthetic cannabinoids JWH-018, JWH-073 and AM2201 were metabolised by the fungus Cunninghamella elegans. In this article, data on individual metabolites of their retention times, mass accuracies, major product ions and structures indicated by product ions are presented. The data in this article is related to "Biotransformation of synthetic cannabinoids JWH-018, JWH-073 and AM2201 by Cunningham...

BACKGROUND K2 products are synthetic cannabinoid-laced, marijuana-like drugs of abuse, use of which is often associated with clinical symptoms atypical of marijuana use, including hypertension, agitation, hallucinations, psychosis, seizures and panic attacks. JWH-018, a prevalent K2 synthetic cannabinoid, is structurally distinct from Δ(9)-THC, the main psychoactive ingredient in marijuana. Sin...

The classical trust region algorithm was extended to the nonsmooth minimization problem successful by Qi and Sun. Combining the trust region algorithm of Qi and Sun and the trust region algorithm with radius bounded below of Jiang for solving generalized complementarity problems, this paper present a new trust region algorithm with radius bounded below for the unconstrained nonsmooth optimizati...