The rate of diffusion of a protein in solution from a source in agar gel is, within limits, proportional to its original concentration (Ouchterlony, 1949). When plasminogen in biological fluids is allowed to diffuse from a source in agar/fibrinogen gel for a given time, the distance diffused can be ascertained by activation of the plasminogen to plasmin by streptokinase after diffusion has take...

Hydrogels are widely studied for chemical sensors. However, they are known to adsorb organic compound and metal ions. The adsorption abilities of hydrogels against organic compounds and metal ions will negatively affect the performance of a hydrogel based chemical sensor. To clarify the effect of hydrophobic pollution on swelling behavior of temperature-sensitive gel, the temperature-responses ...

Novel polymer gel electrolytes have been prepared by incorporating LiI-I(2) solutions into a polyethylene oxide matrix supported by a TiO(2) filler. The gel electrolytes, based on either acetonitrile or propylene carbonate solvents are compared with liquid standard ones and are examined by (7)Li solid state nuclear magnetic resonance relaxometry and diffusion measurements. In parallel, the trii...

The behavior of gel layer thickness in swellable hydroxypropyl methyl cellulose matrices loaded with increasing amounts of soluble and colored drug and exhibiting swelling, diffusion and erosion fronts, was studied using a colorimetric technique. The effect of the drug loading on the front position in the gel layer, in particular, on the presence of a diffusion front and its movement, was inves...

it is over several decades that ultrasound is used to enhance the transdermal drug delivery (phonphoresis). the mechanism of the enhancement is not fully understood and the ability of ultrasound on the enhancement for some drugs is unclear. the effect of continuous wave 870 khz ultrasound at intensity of 1 w/cm 2 for 15 minutes on transdermal absorption of piroxicam from solution and gel formul...

We investigate the effect of the thickness of the silicon nitride (SiN x ) diffusion barrier on the structural and photocatalytic efficiency of TiO2 films obtained with different processes. We show that the structural and photocatalytic efficiency of TiO2 films produced using soft chemistry (sol-gel) and physical methods (reactive sputtering) are affected differentially by the intercalating SiN...

Hydrogels are biocompatible polymeric materials that are becoming increasingly important in biomedical applications, such as drug delivery and tissue engineering. Understanding of small-molecule diffusion in these systems is important in the contexts of controlled drug release; transport of nutrients (e.g., O2 and growth factors) into the gel; and transport of cellular waste out of the gel. In ...

Self-diffusion NMR is used to investigate monodispersed oil in water emulsions and the subsequent gel formed by removing the water through evaporation. The radius of the oil droplets in the emulsions is measured using a number of diffusion methods based on the measurement of the mean squared displacement of the oil, water, and tracer molecules. The results are consistent with the known size of ...

Housing bio-nano guest devices based on DNA nanostructures within porous, conducting, inorganic host materials promise valuable applications in solar energy conversion, chemical catalysis, and analyte sensing. Herein, we report a single-template synthetic development of hierarchically porous, transparent conductive metal oxide coatings whose pores are freely accessible by large biomacromolecule...

A hyaluronic acid-protein complex was embedded into agar gel. This gel complex resembles in some respects the physiological situation in connective tissue, but still permits precise physicochemical measurements to be made. The diffusion coefficient of caffeine into and from such gels has been measured as a function of both agar and hyaluronate concentration. The value for the diffusion coeffici...