discussion the reason is that we assess the relative and not absolute differences of the tracer uptake in this imaging modality. there may be other findings on mpi images which could help us overcome this pitfall, including detecting wall motion abnormalities, lung uptake of the tracer, or transient ischemic dilation. another important issue is the ecg changes during exercise stress testing, wh...

Fixed myocardial defects in both stress and rest images, could be artifactual as a result of soft tissue attenuation. To increase specificity and identify the false positive results, we used gated technique to evaluate the wall motion and wall thickening as an index to differentiate real ischemic lesions from artifactual defects. 93 patients were studied. In 46 patients (48.8%) fixed perf...

BACKGROUND Perfusion-cardiovascular magnetic resonance (CMR) is generally accepted as an alternative to SPECT to assess myocardial ischemia non-invasively. However its performance vs gated-SPECT and in sub-populations is not fully established. The goal was to compare in a multicenter setting the diagnostic performance of perfusion-CMR and gated-SPECT for the detection of CAD in various populati...

UNLABELLED This study investigates the feasibility of routine clinical 201Tl gated perfusion SPECT (gated Tl), and compares quantitative left ventricular ejection fraction (LVEF) and visually-assessed regional wall motion and thickening to analogous values obtained from 99mTc-sestamibi gated perfusion SPECT (gated MIBI). METHODS We studied 121 patients with a rest gated Tl (3-3.5 mCi, 35 sec/...

UNLABELLED We have developed a completely automatic algorithm to quantitatively measure left ventricular ejection fraction (LVEF) from gated 99mTc-sestamibi myocardial perfusion SPECT images. METHODS The algorithm operates in the three-dimensional space and uses gated short-axis image volumes. It segments the left ventricle (LV), estimates and displays endocardial and epicardial surfaces for ...

BACKGROUND The assessment of left ventricular function may be impaired by the abnormal interventricular septal motion frequently found after coronary artery bypass grafting (CABG). Studies on the validation of gated SPECT as a tool for the assessment of left ventricular function in this patient group are scarce. OBJECTIVE We investigated the agreement and correlation between left ventricular ...

Introduction: The aim of this study was to evaluate the effect of successful kidney transplantation (KT) on myocardial perfusion and left ventricular function by both qualitative (visual) interpretation and semiquantitative parameters, using myocardial perfusion scintigraphy with gated-single photon emission computed tomography (gated-SPECT) in patients suffering from end-stage renal disease. ...

UNLABELLED Myocardial perfusion gated-single photon emission computed tomography (gated-SPECT) imaging is used for the combined evaluation of myocardial perfusion and left ventricular (LV) function. The aim of this study is to analyze the influence of counts/pixel and concomitantly the total counts in the myocardium for the calculation of myocardial functional parameters. MATERIAL AND METHODS...

Gated myocardial perfusion SPECT and PET are commonly used to calculate left ventricular ejection fraction (LVEF) and assess left ventricular end diastolic (EDV) and end systolic volumes (ESV). A number of software methods have been developed to automatically calculate these parameters. In a previous work we compared the LV parameters (EF, EDV, ESV) for three software packages: MIMcardiac®, QGS...

Over the course of the last two decades, myocardial perfusion with Single Photon Emission Computed Tomography (SPECT) has emerged as an established and well-validated method for assessing myocardial ischemia, viability, and function. Gated-SPECT imaging integrates traditional perfusion information along with global left ventricular function. Despite of these advantages, inherent limitations of ...