Intensivists are regularly confronted with the question of gastrointestinal bleeding. To date, the latest international recommendations regarding prevention and treatment for gastrointestinal bleeding lack a specific approach to the critically ill patients. We present recommendations for management by the intensivist of gastrointestinal bleeding in adults and children, developed with the GRADE ...

We investigated 2668 patients with non-variceal upper gastrointestinal bleeding and 660 patients with lower gastrointestinal bleeding treated between 1987 and 2011 in our hospital. Upper gastrointestinal bleeding was associated with gastric ulcer, duodenal ulcer, Mallory-Weiss syndrome, esophageal disease, and others. Endoscopic hemostasis was performed in approximately 67% of all cases with up...

• To use clinical clues to differentiate between upper and lower gastrointestinal (GI) hemorrhage • To examine results of vital signs, blood tests, and nasogastric aspirate to assess severity of GI hemorrhage and define immediate resuscitative measures • To define the common causes of GI hemorrhage in the intensive care unit (ICU) • To develop a diagnostic strategy and plan of management • To d...

Gastrointestinal stromal tumours (GIST) are rare gastrointestinal tumours and are one of the causes of obscure gastrointestinal bleeding. We report a case of massive gastrointestinal bleeding secondary to bleeding jejunal GIST in a 43 years old gentleman. Endoscopic intervention failed to identify the source of bleeding and CT Angiography (CTA) showed a jejunal mass and patient underwent laparo...

Acute upper gastrointestinal bleeding (UGIB) is a common indication for upper gastrointestinal endoscopy, with a large audit reporting 14% mortality [1,2]. Although, the gastrointestinal tract is the most common site of the lymphoma, lymphoma is a rare cause of the gastrointestinal bleeding [3]. In this paper, we present a case with non-Hodgkin’s Lymphoma (NHL) resulting in massive gastrointest...

BACKGROUND Gastrointestinal bleeding is the most frequent emergency for gastroenterologists. Despite advances in management, an improvement in mortality is still not evident. AIM Determining time trends of gastrointestinal bleeding hospitalization and outcomes from 2001 to 2010 in the Veneto Region (Italy). PATIENTS AND METHODS Data of patients admitted with gastrointestinal bleeding from V...

OBJECTIVES To determine the association between inhibition of serotonin reuptake by antidepressants and upper gastrointestinal bleeding. DESIGN Retrospective cohort study from population based databases. SETTING Ontario, Canada. PARTICIPANTS 317 824 elderly people observed for more than 130 000 person years. The patients started taking an antidepressant between 1992 and 1998 and were grou...

Background: Selective serotonin reuptake inhibitors (SSRIs) have been associated with depletion of serotonin in platelets, and risk of bleeding. Objective: The main objective is to report the cases of two young males with no medical problems other than their psychiatric disorders presenting with lower gastrointestinal bleeding after paroxetine use. Method: We report two cases of lower gastroint...

OBJECTIVE The association between selective serotonin receptor inhibitors (SSRIs) and risk of upper gastrointestinal bleeding remains controversial. Previous studies have generally evaluated the issue for approximately 3 months, even though the SSRI-mediated inhibition of platelet serotonin concentrations occurs within 7-14 days. The authors explored the risk of upper gastrointestinal bleeding ...