OBJECTIVE To evaluate partial and complete circular duodenectomy combined with highly selective vagotomy (HSV) for relief of gastric retention. DESIGN A retrospective, case-comparison study. SETTING University hospital referral center. PATIENTS Eighteen patients with severe obstructing duodenal ulcer disease defined by failure of a saline load test and endoscopic narrowing of the gastric ...

The objective of this study was to evaluate gastric emptying (GE) in pediatric patients with functional constipation. GE delay has been reported in adults with functional constipation. Gastric emptying studies were performed in 22 children with chronic constipation, fecal retention and fecal incontinence, while presenting fecal retention and after resuming regular bowel movements. Patients (18 ...

EDITORIAL SYNOPSIS The causes of obstruction in 100 cases diagnosed clinically as 'pyloric stenosis' showed that the majority of cases were duodenal ulcer stenosis, with prepyloric carcinoma as second in frequency. In the earlier stages the obstruction is overcome by hyperactivity of the gastric muscle but later on muscular failure occurs with gastric atony and retention of food. This is revers...

BACKGROUND β-cell hyperplasia has been implicated in the aetiology of post Roux-en-Y gastric bypass hyperinsulinaemic hypoglycaemia, but the pathogenesis of this condition is still unclear. CASE REPORT We report a case of a 52-year-old man with post-Roux-en-Y gastric bypass hyperinsulinaemic hypoglycaemia who underwent distal pancreatectomy to alleviate his symptoms. Pancreatic histopathology...

The aim of writing this review on gastro retentive and floating drug delivery system was to compile the new literature with the principle mechanism of floatation to acquired gastric retention. Various attempts have been made to develop gastroretentive delivery systems such as high density system, swelling, floating system. In floating multiple unit and single unit system are design and their cl...

EDITORIAL SYNOPSIS The causes of obstruction in 100 cases diagnosed clinically as 'pyloric stenosis' showed that the majority of cases were duodenal ulcer stenosis, with prepyloric carcinoma as second in frequency. In the earlier stages the obstruction is overcome by hyperactivity of the gastric muscle but later on muscular failure occurs with gastric atony and retention of food. This is revers...

The stomach tube was first used to administer food and medication or to remove poisonous substances. Later, it served to aspirate the stomachs of patients with gastric retention. Chemical analysis of stomach contents after a meal was first suggested in 1871 and quickly became an important laboratory procedure as various test-meal stimuli and more flexible tubes were developed. Quantitative esti...

OBJECTIVE Slowing of gastric emptying by hyperglycemia, a physiological response to minimize postprandial hyperglycemia, may be impaired in patients with type 1 diabetes. The causes and consequences on glucose homeostasis are unknown. RESEARCH DESIGN AND METHODS Consequences of euglycemia- and hyperglycemia-induced changes in gastric emptying on postprandial glucose fluxes and excursions were...

OBJECTIVE To evaluate the natural history of gastric emptying in diabetes. RESEARCH DESIGN AND METHODS Thirteen patients with diabetes (12, type 1; 1, type 2) had measurements of gastric emptying, blood glucose levels, glycated hemoglobin, upper gastrointestinal symptoms, and autonomic nerve function at baseline and after 24.7 ± 1.5 years. RESULTS There was no change in gastric emptying of ...