this prospective study aimed to compare the intraosseous (io) and intravenous (iv) effects of propofol on selected blood parameters and physiological variables during general anesthesia in rabbits. thirty new zealand white rabbits were studied. six rabbits received iv propofol (group 1) and another 6 rabbits, were injected propofol intraosseously (group 2) for 30 minutes (experimental groups). ...

Reference biochemical values for serum analytes of 126 clinically normal farmed ostriches on one farm in Botswana were established. These included sodium, potassium, chloride, total protein, albumin, urea, creatinine, uric acid, cholesterol, total bilirubin, conjugated bilirubin, glucose, triglyceride, calcium, phosphorus, manganese, copper, zinc, alkaline phosphatase, gamma glutamyl transferas...

Two epithelial cell lines designated LE/2 and LE/6 were established from cells isolated by centrifugal elutriation from the livers of carcinogen-treated rats. Both cell lines exhibit some characteristics of fetal liver cells, such as the expression of the 2.3-kilobase alpha-fetoprotein mRNA, aldolase A, and lactate dehydrogenases 4 and 5. Primary cultures contain gamma-glutamyl transferase-posi...

OBJECTIVE To investigate the impact of the baseline status of patients with hepatitis B virus-associated acute-on-chronic liver failure on short-term outcomes. METHODS A retrospective study was conducted that included a total of 138 patients with hepatitis B virus-associated acute-on-chronic liver failure admitted to the Department of Infectious Diseases, Taihe Hospital, Hubei University of M...

BACKGROUND The transcription factor hepatocyte nuclear factor (HNF)-1 alpha regulates the activity of a number of genes involved in innate immunity, blood coagulation, lipid and glucose transport and metabolism, and cellular detoxification. Common polymorphisms of the HNF-1 alpha gene (HNF1A) were recently associated with plasma C-reactive protein and gamma-glutamyl transferase concentration in...

We present a case of traumatic neuroma the common bile duct in 53-year-old woman who presented with jaundice,5months after cholecystectomy. Physical examination revealed jaundice, epigastric pain and scratching lesions. Gamma glutamyl transferase (GGT) at 109 U/L, Alkaline phosphatase 175U/L. CA19-9 was 500U/mlMagnetic resonance cholangiopancreatography T1 T2hyperintense lesion peri-hilar fat. ...

OBJECTIVE Assess the hepatoprotective effect of Taurine (Tau) in cases of hepatic cholestasis induced by Total Parenteral Nutrition (TPN). METHODS We describe a retrospective series of 54 patients who received TPN, in which cholestasis was detected at an (Intermediate) point that separates the duration of TPN into 2 Phases. From this moment -Phase 2- on, and according to clinical criteria, so...

Nephrotoxicity of chemotherapeutics is a major hindrance in the treatment of various tumors. Therefore, test systems that reflect mechanisms of human kidney toxicity are necessary, and to reduce animal testing cell culture based systems have to be developed. One cell type that is of specific interest in this regard are renal proximal tubular epithelial cells, as they reabsorb substances from hu...