This study aims to evaluate the prevalence, risk factors, and relative risk of gallstones and associated disease in patients with ulcerative colitis (UC). Medical records of 311 patients diagnosed with UC between January 2004 and February 2015 were reviewed retrospectively. To assess relative risk, 622 patients matched by age, sex, and body mass index were included as a control group. Gallstone...

Objective: Few studies are available on the association between gallstones and metformin use. The objective of the study was to determine whether metformin use is associated with gallstones. Methods: A population-based retrospective cohort study was conducted using the database of the Taiwan National Health Insurance Program. Subjects of newly diagnosed diabetes mellitus were included from 2002...

Interesting information came from a 10-year study of necropsy findings in South East England. Female gallstone subjects had a higher BMI than controls but males did not. Gallstones were twice as common in those with diabetes. There was no association with heart disease. A third of elderly patients of both sexes had gallstones but most had not had surgery and gallstones were seldom a cause of de...

Interesting information came from a 10-year study of necropsy findings in South East England. Female gallstone subjects had a higher BMI than controls but males did not. Gallstones were twice as common in those with diabetes. There was no association with heart disease. A third of elderly patients of both sexes had gallstones but most had not had surgery and gallstones were seldom a cause of de...

BACKGROUND Whether non-alcoholic fatty liver disease (NAFLD) is a risk factor for gallstones remains uncertain. Few longitudinal or cohort studies have been used to identify this relationship. The aim of this study was to confirm the association between NAFLD and gallstones in a longitudinal cohort of urban dwellers in China. METHODS To elucidate the association between NAFLD and gallstones, ...

PURPOSE To determine risk factors for the development of gallstones and the prevalence of related cholecystectomy in children following hematopoietic cell transplantation (HCT). PATIENTS AND METHODS A retrospective chart review of 1343 patients aged below 18 years old who survived at least 1 year after HCT from 1969 to 2011 was performed. Multivariate Cox regression models were used to estima...

Pigment gallstones are a common clinical complication of sickle cell (SS) disease. Genetic variation in the promoter of uridine diphosphate (UDP)-glucuronosyltransferase 1A1 (UGT1A1) underlies Gilbert syndrome, a chronic form of unconjugated hyperbilirubinemia, and appears to be a risk factor for gallstone formation. We investigated the association between UGT1A1 (TA)(n) genotype, hyperbilirubi...

GASTROINTESTINAL ENDOSCOPY S165 Gallstones are extremely common in Western societies. Approximately l5% of Americans have gallstones, and approximately 650,000 to 700,000 cholecystectomies are performed every year.1. More than 98% of all biliary tract disorders are in some way related to gallstones. Symptoms and complications related to gallstones are among the most costly digestive disorders, ...