Pulmonary alveolar microlithiasis (PAM) is a rare disease with unknown etiology and pathogenesis. It is characterized by diffuse, innumerable, and minute calculi, called microlithiasis in the alveoli. More than half of reported cases are asymptomatic at the time of diagnosis. We describe the first case of PAM in Korea. A 19-yr-old man without respiratory symptoms presented with interstitial thi...

Base excision repair (BER) pathway is one of the repair systems that have an impact on the radiotherapy and chemotherapy for the cancer patients. The molecular pathogenesis of gallbladder cancer is not known extensively. In the present study we investigated whether the expression of AP endonuclease 1 (APE1) and DNA polymerase β (DNA pol β), key enzymes of BER pathway has any clinical ...

Hypertrophic pulmonary osteoarthropathy occurred in a patient with proved pulmonary alveolar microlithiasis, an association not previously reported. Pulmonary alveolar microlithiasis is an uncommon disorder of unknown aetiology, characterised by microliths within the alveoli. Diagnosis is usually made from the radiographic appearance."2 Finger clubbing has been reported in pulmonary alveolar mi...

BACKGROUND Testicular adrenal rest tumors are a benign condition characterized by the presence of remnants of adrenal tissue within the testes that can lead to infertility. Testicular microlithiasis are calculus deposits within the seminiferous tubules. Both are described in congenital adrenal hyperplasia. OBJECTIVES Describe the frequency of testicular adrenal rest tumors and testicular micr...

TOPIC: Diffuse Lung Disease TYPE: Fellow Case Reports INTRODUCTION: Pulmonary alveolar microlithiasis (PAM) is an extremely rare lung disease characterized by the development of calcium phosphate deposits (microliths) within spaces. Genetic mutations in SLC34A2 gene (solute carrier family 34 member 2 gene), which encodes for a sodium-phosphate co-transporter, have been described as cause diseas...

Testicular Microlithiasis (TM) is an infrequent condition recognized by a sonographic pattern of multiple small foci of increased echogenicity measuring 1-3 mm in diameter. These are randomly distributed throughout the testicular parenchyma, in which calcium deposits have been formed into the lumen of seminiferous tubules or have arisen from the tubular basement membrane components [1-6]. Class...