Solutions o f G aC l3 in various ethers have been studied by 7lG a N M R spectroscopy. <S7lG a data indicate tha t the predom inant species in d iethylether and tetrahydrofuran solutions are G aC l3 0 (C 2H 5) 2 and G aC l3 -2 0 C 4 H g, respectively. However, in monoglyme solution disso­ ciation occurs and the product crystallizing from the solution is [c7's-G aCl2(m onoglym e)2]G aC l4 as dem...

Amiodarone hydrochloride, which is used in life-threatening cardiac tachyarrhythmia, has been known to cause amiodarone induced pulmonary toxicity (AIPT) as a complication. In this study we aimed to investigate the clinical value of technetium-99m diethylene triamine penta-acetic acid (DTPA) aerosol lung scintigraphy in patients with AIPT in comparison with gallium-67 (Ga-67) scan. The study gr...

In this paper, a design for a 1 × 4 optical power splitter based on the multimode interference (MMI) coupler in a silicon (Si)-gallium nitride (GaN) slot waveguide structure is presented-to our knowledge, for the first time. Si and GaN were found as suitable materials for the slot waveguide structure. Numerical optimizations were carried out on the device parameters using the full vectorial-bea...

The compounds RE4FeGa(12-x)Ge(x) (RE = Sm, Tb) were discovered in reactions employing molten Ga as a solvent at 850 degrees C. However, the isostructural Y4FeGa(12-x)Ge(x) was prepared from a direct combination reaction. The crystal structure is cubic with space group Imm, Z = 2, and a = 8.657(4) A and 8.5620(9) A for the Sm and Tb analogues, respectively. Structure refinement based on full-mat...

BACKGROUND Various diseases derive from pathologically altered β-cells. Their function can be increased, leading to hyperinsulinism, or decreased, resulting in diabetes. Non-invasive imaging of the β-cell-specific glucagon-like peptide receptor-1 (GLP-1R) would allow the assessment of both β-cell mass and derived tumours, potentially improving the diagnosis of various conditions. We tested thre...

A. Ga-67 is a group IIIA metal which has been used for imaging a variety of solid neoplasms for more than 25 yr. B . Ga-67 imaging of neoplastic disease has shown the greatest utility in imaging lymphoma. The guideline will concentrate on the use of this technique in lymphoma although the technical aspects of image collection and processing may be applied to the imaging of other neoplastic dise...

  Introduction: Gallium-67 citrate has been known as a good infection agent in nuclear medicine for decades. In this work the value of 67Ga-citrate has been investigated in infected animal models using SPECT imaging at optimized/standardized conditions. Methods: The bacterial (Staphylococcus aureus; S.a. and Escherichia coli; E.c.) and fungal (<em...

UNLABELLED We previously found that (67)Ga was more potent and more specific in single-cell kill than other Auger electron emitters and beta-particle emitters, using an anti-CD74 antibody (Ab) (major histocompatibility complex [MHC] class II invariant chain). Because anti-CD74 Abs follow an unusual processing pathway, with rapid delivery in very large amounts to lysosomes, it was important to d...

The enhanced choline uptake and phosphorylation in tumor cells has motivated the development of radiolabeled choline derivatives as diagnostic markers for imaging cell membrane proliferation and noninvasive detection of prostate, brain and breast tumors. In the present work, we report a facile strategy for the synthesis of choline functionalized macrocyclic chelating agent (DO3A-EA-choline) and...

Breast cancer radioimmunoscintigraphy targeting HER2/neu expression is a growing field of work in nuclear medicine research. In this study, trastuzumab was successively labeled with [(67)Ga] GaCl3 after conjugation with DOTA-NHS-ester. The conjugates were purified by molecular filtration, the average number of DOTA conjugated per mAb was calculated and total concentration was determined by spec...