To cite: Patel RV, Jackson P, De Coppi P, et al. BMJ Case Rep Published online: [please include Day Month Year] doi:10.1136/bcr-2013202764 DESCRIPTION A case of giant hiatal hernia (HH) associated with severe gastro-oesophageal reflux disease (GORD) treated by laparoscopic Nissen fundoplication and gastrostomy in an infant with situs inversus totalis (SIT) is reported highlighting the challenge...

BACKGROUND Postoperative intrathoracic wrap migration is the most frequent morphological complication after laparoscopic antireflux surgery. Previous authors have studied the use of prosthetic materials for hiatal closure to prevent recurrence of hiatal hernia and/or postoperative intrathoracic wrap herniation. HYPOTHESIS Patients with prosthetic hiatal closure have a higher rate of short-ter...

Fundoplication is a standard treatment for gastroesophageal reflux disease (GERD) in neurologically impaired children. However, it has a high recurrence rate due to wrap herniation and disruption resulting from the failure or enlargement of the esophageal hiatus suture site. In adult patients with GERD, reinforcement of the sutured esophageal hiatus with a mesh significantly reduces the recurre...

The natural history of fundoplication in young children with gastroesophageal reflux (GER) had not been analyzed previously. The authors reviewed the charts of 160 children who underwent gastric fundoplication (GF) before the age of 2 years (mean age [+/- SD], 9 +/- 7 months; range, 1 week to 2 years), from 1974 to 1992. Reflux was documented by upper gastrointestinal series in 124 patients, by...

Introduction: Asthma and gastroesophageal reflux disease (GERD) have been closely linked, but the association of one with the other is not completely understood. Though GERD contributes to and exacerbates asthma symptoms, best management has not been established. Many asthmatics have subjective and objective findings of GERD, but the use of antireflux medication may not reduce reflux-related as...

Esophagogastric fistula is a rare complication following Nissen fundoplication, with symptoms usually developing within weeks to 3 years postoperatively.1-3 Proposed mechanisms include recalcitrant reflux, erosion of sutures with Teflon pledgets, and damage associated with repeat procedures.1-3 Past reports describe management of the esophagogastric fistulae with antireflux medications, dilatio...

HYPOTHESIS To determine if a hypercontractile esophagus, manifested by high-amplitude peristaltic contractions (HAPCs) or hypertensive lower esophageal sphincter (HLES), affects the outcome of antireflux surgery. DESIGN Case series. Prospectively maintained database. Direct contact with patients. Mean follow-up 28.7 months. SETTING University hospital. PATIENTS Of 643 patients who had ant...

OBJECTIVE The primary aim of this study was to test the widespread assumption that the viability of the gastric fundus is compromised by fundoplication, thereby limiting the use of stomach to reconstruct the upper gastrointestinal tract after esophageal resection. METHODS Between February 1991 and February 2006, a consecutive series of 142 patients with esophageal adenocarcinoma (EADC) underw...

BACKGROUND Post surgical quality of life (QOL) plays an important role in the decision making process for patients. This study evaluated the subjective opinion of those that underwent Nissen fundoplication to correct their symptoms of hiatus hernia. This study was to evaluate the quality of life and symptomatology before and after in those patients that underwent Nissen fundoplication over an 8...