In the course of our search for antimalarial leads from marine algae, four metabolites, sargaquinoic acid, sargahydroquinoic acid, sargaquinal and fucoxanthin, were isolated from the South African alga Sargassum heterophyllum. Fucoxanthin and sargaquinal showed good antiplasmodial activity toward a chloroquine-sensitive strain (D10) of Plasmodium falciparum (IC50 1.5 and 2.0 microM, respectivel...

Fucoxanthin is a carotenoid present in brown microand macro algae, that induces apoptosis or autophagy in cancer cells grown in vitro. In vivo studies confirmed its interest as a natural anticancer compound, as it exerts antitumoral, antimetastatic and antiangiogenic activities in animal models. Studies focused on the pharmacology of fucoxanthin in cancer cells and tumors have revealed that it ...

The purpose of this study was to determine the antioxidant effect of fucoxanthin. After rats were fed a normal fat diet (NF), high fat diet (HF), and high fat with 0.2% fucoxanthin diet (HF + Fxn) for 4 weeks, the markers of oxidative stress and antioxidant capacity like lipid peroxidation, plasma total antioxidant capacity (TAC), and activities of antioxidant enzymes (catalase, superoxide dism...

Fucoxanthin is a natural carotenoid obtained from seaweed which exhibits antioxidant properties. This research aimed to assess whether fucoxanthin, immobilized on aluminum-silicon carrier particles, has toxic effect immune cells. The viability, proliferation, nitric oxide production and myeloperoxidase activity of thymocytes splenocytes mice in vitro were studied. It was shown that increased th...

Macroalgae are one of potential sources for carotenoids, such as fucoxanthin, which are consumed by humans and animals. This carotenoid has been applied in both the pharmaceutical and food industries. In this study, extraction of fucoxanthin from wet brown seaweed Undaria pinnatifida (water content was 93.2%) was carried out with a simple method using liquefied dimethyl ether (DME) as an extrac...

Fucoxanthin is a carotenoid present in the chloroplasts of brown seaweeds. When ingested, it is metabolized mainly to fucoxanthinol by digestive enzymes of the gastrointestinal tract. These compounds have been shown to have many beneficial health effects, including anti-mutagenic, anti-diabetic, anti-obesity, anti-inflammatory and anti-neoplastic actions. In every cancer tested, modulatory acti...

Introduction . Fucoxanthin is one of the main representatives marine carotenoids with a wide range biological activities, including geroprotective effect. The most common source fucoxanthin in food industry diatomic algae (e.g., Phaeodactylum tricornutum). aim work was to summarize and analyze data on mechanisms action fucoxanthin. Materials Methods An analysis scientific research publications ...

Carotenoids have been shown to have beneficial health effects such as pro-vitamin A activity, immune response modulation and anti carcinogenic activity. People consuming diets rich in carotenoids from natural foods, such as fruits and vegetables, are healthier and have lower mortality from a number of chronic illnesses. (cite: Functional food science and defence against reactive oxidative speci...

Fucoxanthin contents of four species of brown seaweeds (Dictyota indica, Padina tenuis, Colpomenia sinuosa and Iyengaria stellata) from intertidal zone of Qeshm Island, Persian Gulf were assessed in summer and winter of 2016. In addition, some physicochemical properties (pH, temperature, salinity and conductivity) of seawater were monitored on the same time. The antibacterial activity of algal ...

The functioning of carotenoids in photosynthesis is discussed in relation to the reaction mechanism. The energy transfer process from the allenic carotenoid, fucoxanthin, to chl a was intensively investigated in the newly isolated fucoxanthin-chl a / c protein assembly (FCPA) from a brown alga Dictyota dichotoma. The transfer time was shorter than 3 ps at 15°C. The energy level responsible for ...