The growth-inhibiting and binary joint effects of 12 antibacterial agents on the freshwater green alga Pseudokirchneriella subcapitata (Korschikov) Hindák were investigated over 72-h exposures. The toxicity values (the median inhibitory concentration value, in micromoles) in decreasing order of sensitivity were triclosan (0.0018)>triclocarban (0.054)>roxithromycin (0.056)>clarithromycin (0.062)...

Hye-Jin Kim, Kyung June Yim, Hyun-Jin Jang, Seong-Joo Hong, Ji Young Jung, Seung Won Nam, Young-Jin Ryu , Choul-Gyun Lee, Su-Hwan Cheon, and Z-Hun Kim. Korean Society for Biotechnology Bioengineering Journal 2023;38:127-34. https://doi.org/10.7841/ksbbj.2023.38.2.127

BACKGROUND Cancer is a leading cause of human death around the world and occurs through the highly complex coordination of multiple cellular pathways. Recent studies have revealed that microalgal extracts exhibit considerable pharmaceutical activities, including those against various cancer cells. Thus, microalgae are promising candidates as novel cancer therapeutic drugs. In this study, we eva...

Cadmium (Cd) toxicity and production of different thiols (phytochelatins, glutathione, gamma-Glu-Cys and cysteine) were studied in the microalga Chlamydomonas moewusii exposed to different concentrations of this metal (1, 2, 4, 6, 8, and 10 mg/L) for 96 h. The inhibitory effect of Cd on growth was demonstrated. The value of EC50 (metal concentration which reduces the population growth to 50% of...

Low hydrocarbon concentrations stimulated the growth of Tetraselmis suecica, whereas higher concentrations (200 ppm) inhibited growth. The content of chlorophyll a in this microalga was affected in a similar way. Crude oil had the most marked effects. Dispersant SEAKLIN-101-NT and mixtures of oil and SEAKLIN-101-NT did not show selective toxicity for the microalga, although inhibitory effects c...

The dried marine microalga Dunaliella tertiolecta was fed to weaning albino rats for 12 days as the sole protein source at a protein level of 12% protein from casein. Plasma cholesterol, triglycerides, and CPK levels were significantly lower in animals given the microalgal diet than in the control group with values 19.12 %, 45.80%, and 43.90% lower, respectively. These results suggest that the ...

In an agroindustrial wastewater pond, a naturally occurring unicellular microalga, Chlorella vulgaris, was closely associated with the terrestrial plant-associative N2-fixing bacterium Phyllobacterium myrsinacearum. When the two microorganisms were artificially coimmobilized in alginate beads, they shared the same internal bead cavities, and the production of five microalgal pigments increased,...