The protein product of the fra-2 gene (Fra-2), a fos-family member, can compete with Fos protein for participation in activating protein-1 (AP-1) transcription factor complexes and each protein can contribute different transactivational consequences to an AP-1 complex. To date, there is limited characterization of fra-2 mRNA expression in the rat forebrain. We examined basal and restraint-induc...

Data Grid provides sharing services for very large data around the world. Data replication is one of the most effective approaches to reduce access latency and response time. In addition to the benefits, replication has costs such as storage and bandwidth consumption, especially when storage space is low and limited. Therefore,  the data replacement should be done wisely. In this p...

Frequency Response Analysis (FRA) technique has been recognized by worldwide utilities as a matured technology to assess the mechanical integrity of power transformers. While some industrial critical assets such induction motors have same construction principle transformers, application FRA not yet fully explored. This paper presents analogical experimental studies for on transformers and motor...

Individual brainstem neurons involved in vestibular reflexes respond to identical head movements with a wide range of firing responses. This diversity of firing dynamics has been commonly assumed to arise from differences in the types of vestibular nerve inputs to vestibular nucleus neurons. In this study we show that, independent of the nature of inputs, the intrinsic membrane properties of ne...

At present, the condition assessment of transformer winding based on frequency response analysis (FRA) measurements demands skilled personnel. Despite many research efforts in last decade, there is still no definitive methodology for interpretation and FRA results, this a major challenge industrial application method. To overcome challenge, paper proposes (TCA) algorithm, which numerical indice...

Accumulating evidence supports the idea that two known phosphatidylinositol 3'-kinase (PI3K) downstream proteins, Fra-1 and Survivin, are potential targets for cancer therapy. Increased expression of Fra-1, a Fos family member of the transcription factor activator protein-1, has been implicated in both the maintenance and the progression of the transformed state of several cancer cells. In addi...

We analyzed the metacarpophalangeal pattern profile (MCPP) on 18 male individuals from 16 families with fragile X--fra (X), or Martin-Bell--syndrome and calculated a mean syndrome profile. Fourteen of 18 individuals with fra (X) syndrome had significant positive correlations which indicated clinical homogeneity. Discriminant analysis of individuals with fra (X) syndrome compared with a sample o...

Structure-function analysis as well as studies with knock-out and transgenic mice have assigned distinct functions to c-Fos and Fra-1, two components of the transcription factor AP-1 (activator protein-1). To test whether Fra-1 could substitute for c-Fos, we generated knock-in mice that express Fra-1 in place of c-Fos. Fra-1 rescues c-Fos-dependent functions such as bone development and light-i...

Chronic stress is associated with occurrence of many mental disorders. Previous studies have shown that dendrites and spines of pyramidal neurons of the prefrontal cortex undergo drastic reorganization following chronic stress experience. So the prefrontal cortex is believed to play a key role in response of neural system to chronic stress. However, how stress induces dynamic structural changes...

bstract—The protein product of the fra-2 gene (Fra-2), a os-family member, can compete with Fos protein for particpation in activating protein-1 (AP-1) transcription factor omplexes and each protein can contribute different transctivational consequences to an AP-1 complex. To date, here is limited characterization of fra-2 mRNA expression n the rat forebrain. We examined basal and restraint-inu...