Frankincense extracts and boswellic acids, biologically active pentacyclic triterpenes of frankincense, block leukotriene biosynthesis and exert potent anti-inflammatory effects. Screening for additional effects of boswellic acids on further proinflammatory pathways, we observed that acetyl-11-keto-beta-boswellic acid, an established direct, nonredox and noncompetitive 5-lipoxygenase inhibitor,...

Frankincense is an oleo-gum-resin collected from wild Boswellia spp. trees, and widely used in perfumery, cosmetics, aromatherapy, incense, other industries. rivae, growing Ethiopia, Somalia, Kenya, one source of frankincense, but little-commercialized compared to species such as B. sacra, frereana, papyrifera. In this study, we examine the resin essential oil chemistry harvesting systems rivae...

Boswellia carterii, known as frankincense, is a fragrant medicinal plant. The essential oil from this plant often used in traditional medicine or aromatherapy. Due to its positive properties, it has potential applications an antimicrobial agent and the food industry. aim of study was evaluate antimicrobial, anti-insect, antioxidant activities frankincense (FEO). composition volatile compounds d...

Antibiotic resistance is emerging at an alarming rate, outpacing current research and development efforts to combat this trend. As a result, many infectious diseases have become difficult to treat; in some cases, no treatment options exist. The search for new antibiotics must accelerate to avoid returning to the ‘pre-antibiotic’ era. Ancient remedies, including essential oils and their componen...

on a Sumerian clay tablet dating from about 2500 B.C. It describes the cleansing of wounds with water and milk followed by a dressing with honey and resin. The Egyptians discovered that a closed wound will heal faster than a wound which is left open. They devised an adhesive dressing by applying gum to linen strips which were applied to draw the edges of an open wound together. The Ebers papyru...

A new boswellic acid derivative, 11α-ethoxy-β-boswellic acid (EBA; 1) and a new ursane-type triterpene, named nizwanone (2), were isolated from Omani frankincense Boswellia sacra Flueck. together with two known compounds papyriogenin B and rigidenol. The structures of 1 and 2 were elucidated by detailed spectroscopic analysis using (1) H- and (13) C-NMR, (1) H,(1) H-COSY, HMQC, HMBC, and HR-EI-...

The immunomodulatory bioassay-guided fractionation of the oleogum resin of frankincense (Boswellia carterii Birdwood) resulted in the isolation and identification of 9 compounds; palmitic acid and eight triterpenoids belonging to lupane, ursane, oleanane, and tirucallane skeleta were isolated form the resin. These triterpenoids are lupeol, beta-boswellic acid, 11-keto-beta-boswellic acid, acety...