The knee adduction moment (KAM) is a surrogate measure for medial compartment knee loading and is related to the progression of knee osteoarthritis. Toe-in and toe-out gait modifications typically reduce the first and second KAM peaks, respectively. We investigated whether assigning a subject-specific foot progression angle (FPA) modification reduces the peak KAM by more than assigning the same...

ALNOWIBET, KHALID ABDULAZIZ Nonstationary Erlang Loss Queues and Networks. (Under the direction of Dr. Harry Perros) The nonstationary Erlang loss model is a queueing system consisting of a finite number of servers and no waiting room with a nonstationary arrival process or a time-dependent service rate. The Erlang loss model is commonly used to model and evaluate many communication systems. Of...

Background: Software size is one of the key factors that has the potential to affect the effort of software projects. Providing accurate software size estimation is a complex task. A number of functional size measurement (FSM) methods have been proposed to quantify the size of software based on functional user requirements (user perspective). Function point analysis (FPA) was the first proposal...

Function Point Analysis (FPA) is used by organisations worldwide as one of the measures used to establish the baseline size of their software assets in outsourcing contracts. This paper introduces new techniques, which enable all the functionality delivered and worked on by the supplier to be included in the productivity performance monitoring of these contracts. Typically only the business app...

RNA-binding proteins (RBPs) play an important role in plant host-microbe interactions. In this study, we show that the plant RBP known as FPA, which regulates 3'-end mRNA polyadenylation, negatively regulates basal resistance to bacterial pathogen Pseudomonas syringae in Arabidopsis. A custom microarray analysis reveals that flg22, a peptide derived from bacterial flagellins, induces expression...

Fluorescence polarization analysis (FPA) of a liquid-phase method was carried out with a glycosylphosphatidylinositol (GPI) anchored membrane receptor bone marrow stromal cell antigen 1 (BST-1, CD157) as a model receptor for medical screening. A soluble receptor, BST1-Fc, was prepared by fusing the extracellular domain of BST-1 and the Fc region of human immunoglobulin G (IgG). The binding curv...

Despite the proven applicability of the statistical methods in automatic fault localization, these approaches are biased by data collected from different executions of the program. This biasness could result in unstable statistical models which may vary dependent on test data provided for trial executions of the program. To resolve the difficulty, in this article a new ‘fault-proneness’-aware s...

Classical hemophilia results from a defect of the intrinsic tenase complex, the main factor X (FX) activator. Binding of factor VIIa to tissue factor triggers coagulation, but little amplification of thrombin production occurs. Handling of hemophilia by injection of the deficient or missing (thus foreign) factor often causes immunological complications. Several strategies have been designed to ...

Anatomical and physiological studies have shown that the "frontal pursuit area" (FPA) in the arcuate cortex of monkeys is involved in the control of smooth pursuit eye movements. To further analyze the signals carried by the FPA, we examined the activity of pursuit-related neurons recorded from a discrete region near the arcuate spur during a variety of oculomotor tasks. Pursuit neurons showed ...

To provide more information on the pathways of fibrinogen catabolism in generalized cancer. the effect of heparin on fibrinopeptide A (fpA) and on 1251-fibrinogen kinetics was studied in 1 5 patients with disseminated neoplasia. Three patients had evidence of venous thrombosis and in 2 additional patients a low fibrinogen level together with increased amounts of FDP/fdp and a positive ethanol t...