Albinism, an inherited disorder of melanin biosynthesis, disrupts normal retinal development, with foveal hypoplasia as one of the more commonly associated ocular phenotypes. However the cellular integrity of the fovea in albinism is not well understood - there likely exist important anatomical differences that underlie phenotypic variability within the disease and that also may affect responsi...

PURPOSE To assess the reproducibility of retinal thickness measurements in normal subjects and to compare foveal thickness using optical coherence tomography (OCT) and the scanning retinal thickness analyzer (RTA). METHODS Two examiners performed foveal thickness measurements in 24 eyes of 12 healthy subjects using both OCT and the scanning RTA. Intraclass correlation coefficients (ICC) (intr...

PURPOSE When individuals with central vision loss due to macular degeneration (MD) view stimuli in the periphery, most of them activate the region of retinotopic cortex normally activated only by foveal stimuli-a process often referred to as reorganization. Why do some show this reorganization of visual processing whereas others do not? We reported previously that six individuals with complete ...

During reading, we can process words allocated to the parafoveal visual region. Our ability extract information is determined by availability of attentional resources, and how these are distributed among in field. According foveal load hypothesis, a greater difficulty processing word would result less resources being word, thereby hindering its processing. However, contradictory results have ra...

BACKGROUND Recent reports indicated that the slope of the foveal depression influences the macular pigment (MP) spatial profile. MP has been shown to confer possible protection against age-related macular degeneration (ARMD) because of its antioxidant properties. AIMS To study the configuration of foveal slope and the foveal thickness in fellow eyes of subjects with unilateral neovascular ARMD....

PURPOSE To evaluate the clinical course of visual acuity and foveal thickness in the idiopathic epiretinal membrane (ERM) after a vitrectomy with the use of triamcinolone. METHODS We retrospectively reviewed the records of 30 patients (30 eyes) with ERM that were treated by vitrectomy from 2004 to 2008. Visual acuity and foveal thickness from optical coherence tomography imaging was obtained ...