The Bethesda System for Reporting Thyroid Cytology (TBSRTC) has proven to be an effective and robust thyroid fine needle aspiration (FNA) classification scheme to guide the clinical treatment of patients with thyroid nodules. However, a tendency of increasing diagnosis of atypia of undetermined significance/follicular lesion of undetermined significance (AUS/FLUS) is observed. This is commensur...

Follicular patterned lesions of the thyroid are problematic and interpretation is often subjective. While thyroid experts are comfortable with their own criteria and thresholds, those encountering these lesions sporadically have a degree of uncertainty with a proportion of cases. The purpose of this review is to highlight the importance of proper diligent sampling of an encapsulated thyroid les...

common site for the presentation of extranodal non-Hodgkin’s lymphoma. Depending on the series, follicular lymphoma of the gastrointestinal tract accounts for 3.6 % of gastrointestinal lymphoma [1]. Above all, follicular lymphoma shows a predilection for the duodenum, where 55.6 %– 62.5 % of cases are located [1,2]. We present the case of a 47-year-old woman with epigastralgia. An elevated lesi...

Follicular occlusion triad (FOT) is a complex chronic inflammatory skin disease comprising hidradenitis suppurativa (HS), acne conglobata (AC), and dissecting cellulitis of the scalp (DCS; Hoffman’s or perifolliculitis capitis abscedens et suffodiens). While pathological mechanisms are responsible for common manifestations, exact underlying causes follicular have not yet been clearly identified...

The aim of this study was to evaluate the relationship between abnormal expression of E-cadherin (E-CAD) and the extracapsular extension of tumors, lymph node involvement and the presence of metastasis in various types of thyroid cancers. Histopathological specimens of 35 benign thyroid lesions and 122 malignant tumors (papillary, follicular, poorly differentiated and undifferentiated cancers) ...

Follicular mucinosis is characterized by mucin deposits within the hair follicles and sebaceous glands. It can occur as a primary idiopathic benign disorder; it can be found as an incidental phenomenom in rare cases of different dermatoses; or it can arise as a secondary symptom of a malignant disorder, most commonly mycosis fungoides. Youth and localization in a single area used to be regarded...

We studied the differentiation of thyroid nodules using fine-needle aspiration biopsy (FNA) and Tl-201 scintigraphy quantitative analysis. One-hundred and thirty-one thyroid nodules were examined: 83 follicular lesions (58 benign and 25 malignant lesions) and 48 non-follicular lesions (8 benign and 40 malignant lesions). During Tl-201 scintigraphy examinations, an early and a delayed image were...

HYPOTHESIS The application and reliability of fine-needle aspiration (FNA) biopsy in community hospitals may be less efficacious in the clinical assessment of patients with thyroid nodules than in tertiary referral centers. DESIGN Retrospective review. SETTING One community teaching hospital. PATIENTS One hundred eighty-three patients who underwent thyroidectomy after FNA biopsy. INTERV...

To determine the content of thyroglobulin in oxyphilic cells of the thyroid, which have been considered as non-thyroglobulin producing cells, the degree of stainability of the various oxyphilic cells for thyroglobulin was compared with that of non-oxyphilic follicular cells in either same or different lesion. A total of 13 oxyphilic lesions, including three follicular adenomas containing oxyphi...