OBJECTIVE To devise a strategy for prevention of beta thalassemia in newborns through reliable screening of indexed families. METHODS The cross-sectional study was conducted over six months in 2011 and comprised blood samples collected from subjects belonging to different ethnic groups from families of beta thalassemia major children registered with the Abbottonian Medical Association Blood C...

A general technique is described for using slide-mounted unfixed tissue sections to characterize and visualize drug and neurotransmitter receptors in brain or other tissues. The preparation of material, from fresh frozen, unfixed brain to dried sections securely attached to slides, is described in detail. The tissue can be kept intact during incubation at varying temperatures in solutions conta...

Background: Lung densitometry derived from computed tomographic images offers an opportunity to quantify emphysema non-invasively, but a pathological standard cannot be applied to validate its use in longitudinal monitoring studies. Consequently, forced expiratory volume in 1 second (FEV1) remains the standard against which new methods must be judged. We related progression of densitometry (15t...

Body composition was measured in nine healthy, normal-weight, weight-stable subjects in three different research centres. In each centre the usual procedures for the measurements were followed. It revealed that the measurement procedures in the three centres were comparable. Body composition was measured in each centre between 09.00 and 13.00 hours after a light breakfast by densitometry (under...

failure of antigen production is more likely to be due to genetic change associated with incomplete penetrance than to genetic loss. An alternative or additional possibility cannot, however, be excluded-that exuberant cell division causes dilution of a particulate cytoplasmic factor responsible for the formation of the antigen. Loss of organ-specific antigens could influence tumour metastasis b...

BACKGROUND Lung densitometry derived from computed tomographic images offers an opportunity to quantify emphysema non-invasively, but a pathological standard cannot be applied to validate its use in longitudinal monitoring studies. Consequently, forced expiratory volume in 1 second (FEV1) remains the standard against which new methods must be judged. We related progression of densitometry (15th...

X-rays were initially used for the inspection of special-purpose wood pieces for quantitative evaluation of wood properties of different species. X-ray densitometry has had its use expanded in dendroclimatology of Picea engelmannii trees. Subsequent laboratories developed applications of X-ray densitometry for environmental, wood science and technology, and related areas. This paper describes t...

CONTEXT AND OBJECTIVE Identification of women at risk of bone fracture is becoming less dependent on evaluating bone mineral density through placing greater value on clinical risk factors. The aim of this study was to evaluate the sensitivity of the Osteorisk clinical tool for identifying Brazilian postmenopausal women with osteoporosis, compared with bone densitometry. DESIGN AND SETTING Cro...