BACKGROUND Diastolic dysfunction is a major pathophysiological abnormality in hypertrophic cardiomyopathy (HCM). Doppler echocardiographic parameters correlate with left ventricular (LV) filling pressures in other diseases, but it is unclear whether these findings apply to patients with HCM, who have multiple complex interrelated events leading to diastolic dysfunction. This study compares Dopp...

INTRODUCTION AND OBJECTIVES In patients with systolic dysfunction, different ventricular filling patterns are associated with different prognoses. The load changes resulting from nitroprusside infusion or long-term therapy for heart failure induce alterations in filling pattern that have been shown to serve as outcome markers. Our aim was to investigate the prognostic value of the Doppler-detec...

was recorded simultaneously with pulsed Doppler echocardiography of left ventricular inflow and M-mode echocardiography of left ventricular diameter. Chamber stilfness constants, kd and k1, were obtained from the diastolic pressure-diameter and pressure-volume relations, respectively. Relaxation was measured by the isovolumic relaxation time constants, TL and TD, derived from the exponential le...

was recorded simultaneously with pulsed Doppler echocardiography of left ventricular inflow and M-mode echocardiography of left ventricular diameter. Chamber stilfness constants, kd and k1, were obtained from the diastolic pressure-diameter and pressure-volume relations, respectively. Relaxation was measured by the isovolumic relaxation time constants, TL and TD, derived from the exponential le...

Method 23 patients with STEMI undergoing primary PCI were prospectively enrolled and sequential CMR imaging was performed within 96 hours of admission and at 1 month follow up. LV volumetric quantification was performed (QMass MR, Medis, Leiden, The Netherlands) with manual planimetry of the endocardial contours in all temporal phases of the contiguous short-axis slices. Systolic parameters wer...

We present a systematic study of capillary filling for multi-phase flows by using mesoscopic lattice Boltzmann models describing a diffusive interface moving at a given contact angle with respect to the walls. We compare the numerical results at changing the density ratio between liquid and gas phases, δρ/ρ and the ratio, δξ/H , between the typical size of the capillary, H , and the interface w...