The number of fully sequenced fungal genomes is rapidly increasing. Since genetic tools are poorly developed for most filamentous fungi, it is currently difficult to employ genetic engineering for understanding the biology of these fungi and to fully exploit them industrially. For that reason there is a demand for developing versatile methods that can be used to genetically manipulate non-model...

The typical life cycle of filamentous fungi commonly involves asexual sporulation after vegetative growth in response to environmental factors. The production of asexual spores is critical in the life cycle of most filamentous fungi. Normally, conidia are produced from vegetative hyphae (termed mycelia). However, fungal species subjected to stress conditions exhibit an extremely simplified asex...

Keratinophilic fungi include a variety of filamentous fungi mainly comprising hyphomycetes and several other taxonomic groups. Hyphomycetes include dermatophytes and a great variety of nondermatophytic filamentous fungi. Most of the latter occur as saprophytes in soil, and some are plant pathogens. Chrysosporium species are the commonest nondermatophytic filamentous fungi and are predominantly ...

Mycotoxins are toxic secondary metabolites produced by filamentous fungi belonging, in particular, to the Aspergillus, Fusarium, and Penicillium genera [...]

Carbon Catabolite Repression (CCR) has fascinated scientists and researchers around the globe for the past few decades. This important mechanism allows preferential utilization of an energy-efficient and readily available carbon source over relatively less easily accessible carbon sources. This mechanism helps microorganisms to obtain maximum amount of glucose in order to keep pace with their m...

Filamentous fungi possess unique features which make them attractive as hosts for the production of heterologous gene products. For example, certain fungal species are capable of secreting large quantities of protein in submerged culture. Selected strains of Aspergillus niger can produce greater than 20 g of glucoamylase I ~ I in industrial fermentations [ 11. Some filamentous fungi, including ...

BACKGROUND Filamentous fungi and bacteria form mixed-species biofilms in nature and diverse clinical contexts. They secrete a wealth of redox-active small molecule secondary metabolites, which are traditionally viewed as toxins that inhibit growth of competing microbes. RESULTS Here, we report that these "toxins" can act as interspecies signals, affecting filamentous fungal development via ox...

Antimicrobial activity of different culture extract of Oudemansiella sp grown on liquid medium (MYGP) were tested. Different fungi (C. albicans, C. lipolytica, Saccharomyces cervisiea, Cladosporium herbarum, and Aspergillus niger) and bacteria (Microccocus luteus, E. coli, Staphylococcus aureus, and Staphylococcus epidermidis) were used as test organisms. Various antimicrobial assay metho...

Antimicrobial activity of different culture extract of Oudemansiella sp grown on liquid medium (MYGP) were tested. Different fungi (C. albicans, C. lipolytica, Saccharomyces cervisiea, Cladosporium herbarum, and Aspergillus niger) and bacteria (Microccocus luteus, E. coli, Staphylococcus aureus, and Staphylococcus epidermidis) were used as test organisms. Various antimicrobial assay metho...

In the production of industrial enzymes, filamentous fungi are attractive as cell factories because they can secrete large amounts of protein into the medium. Many important industrial enzymes such as amylases, lipases and cellulase are produced by fermentation of filamentous fungi. Aspergillus oryzae is well-known filamentous producer of alpha amylase and has GRAS status. In the present study ...