نتایج جستجو برای: fibroblast growth factor receptor 1

تعداد نتایج: 4133312  

Journal: :The Journal of Cell Biology 1990
B B Olwin S D Hauschka

Two putative receptors for fibroblast growth factor (FGF) of approximately 150 and 200 kD were identified in membrane preparations from chick embryos. Specific binding (femtomoles/milligram) of 125I-aFGF to whole chick embryonic membranes was relatively constant from day 2 to 7, then decreased fivefold between days 7 and 13. Day-19 chick embryos retained 125I-aFGF binding at low levels to brain...

Journal: :The Journal of clinical investigation 2007
Lars Johan Nissen Renhai Cao Eva-Maria Hedlund Zongwei Wang Xing Zhao Daniel Wetterskog Keiko Funa Ebba Bråkenhielm Yihai Cao

Tumors produce multiple growth factors, but little is known about the interplay between various angiogenic factors in promoting tumor angiogenesis, growth, and metastasis. Here we show that 2 angiogenic factors frequently upregulated in tumors, PDGF-BB and FGF2, synergistically promote tumor angiogenesis and pulmonary metastasis. Simultaneous overexpression of PDGF-BB and FGF2 in murine fibrosa...

Journal: :international journal of pediatrics 0
maria francis yuvaraj instructor, phd candidate, department of anatomy, saveetha medical college, thandalam, chennai, india. ponuswamy kasirajan sankaran associate professor, department of anatomy, saveetha medical college, thandalam, chennai, india. gunapriya raghunath professor, department of anatomy, saveetha medical college, thandalam, chennai, india. zareena begum kumaresan instructor, phd candidate, department of anatomy, saveetha medical college, thandalam, chennai, india. kumaresan kumaresan m instructor, phd candidate, department of anatomy, saveetha medical college, thandalam, chennai, india.

the rare form of skeletal dysplasia is thanatophoric dysplasia. the meaning for thanatophoric dysplasia is death bearing which is derived from greek word. it occurs 1in 20,000 to 50,000. it is mainly due to mutations in the fibroblast growth factor receptor 3gene. features of thanatophoric dysplasia are frontal bossing, prominent eyes, narrow thorax, protruded abdomen and bowed legs. the knowle...

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