fibroadenoma of the vulva is an uncommon lesion. it has been suggested that they originate from vulvar mammary like other glands. a few examples of benign and malignant vulvar tumors arising from such glands have been reported. a 32-year-old woman was referred with a subcutaneous mass at the vulva. the patient treated by simple excisional surgery with adequate peripheral margin. histological fi...

INTRODUCTION Giant fibroadenoma is a rare disease with unknown etiology. During pregnancy, fibroadenomas increase in size and may show lactational histologic changes. High concentrations of estrogen, progesterone, and prolactin promote the ductal growth and formation of tubuloalveolar structures. This may be a reason for the significant enlargement in this period. CASE PRESENTATION We present...

We report an extremely rare case with a total of 50 fibroadenomas simultaneously presented in bilateral breasts and left axillary accessory breast, up to 8 cm in size, in a 20 year-old Chinese woman. The histopathologic and immunophenotypic features of the fibroadenomas are described and possible underlying pathogenesis is discussed. To our knowledge, this is the first case with such a large nu...

the major controversies in breast imaging, though the most important goal of breast ultrasound is to avoid unnecessary surgery. Many reports describing the findings of ultrasound have stated that most solid breast lesions have the characteristics of both benign and malignant m a s s e s ( 1-4). Approximately 10-17% of malignancies have well circumscribed margins(5,6), whereas some benign lesion...

Infarction is an uncommon event in a fibroadenoma, which is the commonest benign tumor of the breast. Most often it occurs in pregnancy, lactation or is secondary to fine needle aspiration. Spontaneous infarction of a fibroadenoma in the absence of a predisposing condition is very rare. The cytopathologic features of infarction are necrosis and worrisome nuclear features, which are often misint...

The present study describes the ultrasonographic and histopathological evaluation of a rare mammary fibroadenoma in 11 month-old buffalo heifer. A homogenous large mammary mass approximately 17 cm was developed in the left rear quarter. The buffalo was assigned for curative surgical removal of the mass. The lesion was well demarcated smooth encapsulated lobular structure, which had a solid cons...

Objective: Oncoplastic surgery was developed to allow for large tumor excision and immediate breast reconstruction with the goal of optimal breast shape and symmetry. Although initially used in women who underwent lumpectomy for breast malignancy, these techniques can be useful for cosmetic issues caused by benign breast disease. We describe a modification of an inferior pedicle with Wise-patte...

CONTEXT Supernumerary breast tissue may be affected by the same diseases and alterations that compromise topical breast tissue. Nevertheless, reports of fibroadenoma in supernumerary breast tissue in the axillae are rare. OBJECTIVE To describe a case of fibroadenoma in an axillary supernumerary breast. DESIGN Case report. CASE REPORT A 39-year-old woman was referred to the gynecology and ...

microRNAs (miRNAs) play an important role in cancer prognosis. They are small molecules, approximately 17-25 nucleotides in length, and their high stability in human serum supports their use as novel diagnostic biomarkers of cancer and other pathological conditions. In this study, we analyzed the expression patterns of miR-21 and miR-221 in the serum from a total of 100 Egyptian female subjects...