نتایج جستجو برای: fibrinolysis
تعداد نتایج: 4662 فیلتر نتایج به سال:
Fibrinolytic therapy of venous thromboembolism (VTE) is increasingly utilized, yet limited knowledge is available regarding in vivo mechanisms that govern fibrinolytic efficacy. In particular, it is unknown how age-dependent thrombus organization limits direct blood contact with fibrin, the target of blood-based fibrinolytic agents. Utilizing high-resolution in vivo optical molecular imaging wi...
Since the late 1980s, fibrinolysis has been the reperfusion therapy most frequently used in patients with ST-segment elevation acute infarction. However, during the last decade, primary percutaneous coronary intervention (PCI) has become the strategy of choice because, by comparison with fibrinolysis, it associates with significantly lower rates of reinfarction (3% vs 7%), 30-day mortality (5% ...
Purulent pericarditis (PP) is a potentially life-threatening disease. Reported mortality rates are between 20 and 30%. Constrictive pericarditis occurs over the course of PP in at least 3.5% of cases. The frequency of persistent PP (chronic or recurrent purulent pericardial effusion occurring despite drainage and adequate antibiotherapy) is unknown because this entity was not previously classif...
Reperfusion therapy has represented a great leap forward in the management of myocardial infarction with ST-segment elevation. Its goal is early and complete recanalization of the infarct-related artery to salvage myocardium and improve both early and late clinical outcomes. Complete reperfusion can be achieved with either fibrinolysis or primary percutaneous coronary intervention (PCI), but wi...
Objective: To evaluate the safety and efficacy of local intra-arterial fibrinolysis with tissue plasminogen activator (tPA) in the management of patients with central retinal artery occlusion. Design: Prospective randomized multicenter clinical trial (the European Assessment Group for Lysis in the Eye study). Methods: 9 centers in Austria and Germany recruited 84 patients with central retinal a...
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