نتایج جستجو برای: fibrin hydrogel

تعداد نتایج: 25282  

Journal: :Bioengineering 2023

Traumatic injuries are a major cause of morbidity and mortality worldwide; however, there is limited research on microvascular traumatic injuries. To address this gap, aims to develop optimise an in vitro construct for injury at the level. Tissue engineering constructs were created using range polymers (collagen, fibrin, gelatine), solvents (PBS, serum-free endothelial media, MES/NaCl buffer), ...

Journal: :Bio-design and manufacturing 2022

Abstract Composites offer the option of coupling individual benefits their constituents to achieve unique material properties, which can be extra value in many tissue engineering applications. Strategies combining hydrogels with fibre-based scaffolds create constructs enhanced biological and structural functionality. However, developing efficient scalable approaches manufacture such composites ...

Journal: :international journal of pediatrics 0
ensiyeh hajizadeh department of stem cells and developmental biology at the cell science research center, royan institute for stem cell biology and technology, acecr, tehran, iran. yaser tahamtani department of stem cells and developmental biology at the cell science research center, royan institute for stem cell biology and technology, acecr, tehran, iran. mohammad ali shokrgozar national cell bank, pasteur institute of iran, tehran, iran. harry heimberg diabetes research center, vrije university of brussels, brussels, belgium. yves heremans diabetes research center, vrije university of brussels, brussels, belgium. philippe ravassard biotechnology and biotherapy laboratory, university pierre et marie curie, paris, france.

background: pancreatic islet transplantation has emerged as a promising treatment for type i diabetes. however, its efficacy is severely hampered due to poor islet engraftment and revascularization, which have been resulted to partially loss of transplanted islets. it has been shown that local delivery of vascular endothelial growth factor (vegf) could accelerate transplanted islet revasculariz...

Journal: :Journal of the Royal Society, Interface 2014
Luca Gasperini João F Mano Rui L Reis

The encapsulation of living mammalian cells within a semi-permeable hydrogel matrix is an attractive procedure for many biomedical and biotechnological applications, such as xenotransplantation, maintenance of stem cell phenotype and bioprinting of three-dimensional scaffolds for tissue engineering and regenerative medicine. In this review, we focus on naturally derived polymers that can form h...

Journal: :Microvascular research 2015
Julie A Rytlewski M Alejandra Aldon Evan W Lewis Laura J Suggs

Stem cell-based therapies are a promising new avenue for treating ischemic disease and chronic wounds. Mesenchymal stem cells (MSCs) have a proven ability to augment the neovascularization processes necessary for wound healing and are widely popular as an autologous source of progenitor cells. Our lab has previously reported on PEGylated fibrin as a unique hydrogel that promotes spontaneous tub...

Journal: :World neurosurgery 2012
Joshua W Osbun Richard G Ellenbogen Randall M Chesnut Lawrence S Chin Patrick J Connolly G Rees Cosgrove Johnny B Delashaw John G Golfinos Jeremy D W Greenlee Stephen J Haines Jack Jallo J Paul Muizelaar Anil Nanda Mark Shaffrey Mitesh V Shah John M Tew Harry R van Loveren Martin E Weinand Jonathan A White James E Wilberger

OBJECTIVE Incisional cerebrospinal fluid (CSF) leakage after cranial surgery is a significant cause of morbidity due to poor wound healing and infection, meningitis, and pseudomeningocele formation. Many common dural closure techniques, such as sutures, autologous grafts, gelatin or collagen sponges, and fibrin glues, are used to achieve watertight closure, although none are US Food and Drug Ad...

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