نتایج جستجو برای: fetal protein
تعداد نتایج: 1309831 فیلتر نتایج به سال:
BACKGROUND & AIMS Hepatocyte-like cells (HLCs), differentiated from pluripotent stem cells by the use of soluble factors, can model human liver function and toxicity. However, at present HLC maturity and whether any deficit represents a true fetal state or aberrant differentiation is unclear and compounded by comparison to potentially deteriorated adult hepatocytes. Therefore, we generated HLCs...
BACKGROUND Myocardial dysfunction occurs in a variety of fetal disorders. Findings from adult cardiology, where n-terminal pro-B-type natriuretic peptide (nt-proBNP) is an established biomarker of left ventricular dysfunction have been extended to fetal life. Since fetal blood sampling is technically challenging we investigated amniotic fluid nt-proBNP for its suitability to diagnose fetal myoc...
Background: Breast cancer is one of the most common cancers in women. Nearly 30% of breast cancers are hormone-dependent, and these hormones comprising estrogens influence progression of breast cancers. It is now widely recognized that p53 may be the most frequently mutated protein in breast cancer. High levels of p53 protein are a common feature of many human malignant cancers. Given that, T47...
The concentration and electrophoretic pattern of serum proteins of the fetus differ from those of the adult in animals (1-3) as well as in man (4-7). In early fetuses of some species, serum proteins have been described which are either absent or modified at later stages of development (8, 9). Pedersen (10) first recognized in the newborn calf a large amount of an unusual a-globulin for which he...
Objectives of this study were to evaluate maternal and fetal influences on development of gravid uterine tissues of cows. Brahman cows with Brahman or Charolais fetuses and Charolais cows with Brahman or Charolais fetuses were used. Cows were killed 232 +/- .5 or 271 +/- .7 d after mating. The gravid uterus of each cow was weighed and dissected into its component parts. Weights of the fetus, fe...
Abstract Hematopoiesis, the process which generates blood cells, changes significantly during mammalian development. Fetal hematopoiesis primarily takes place in fetal liver (FL), where hematopoietic stem cells (FL HSCs) are characterized by high self-renewal capacity and a distinctive program of multilineage differentiation. After birth, main location is bone marrow (BM), (BM less proliferativ...
nowadays, new advances in the use of cell free fetal dna (cffdna) in maternal plasma of pregnant women has provided the possibility of applying cffdna in prenatal diagnosis as a non-invasive method. in contrary to the risks of invasive methods that affect both mother and fetus, applying cffdna is proven to be highly effective with lower risk. one of the applications of prenatal diagnosis is fet...
275+72 mg/dl, P < 0.05) and fetal glucose (64+6 vs. 274±47 mg/dl, P < 0.001) compared with salineinjected diabetic (D) mothers. Reduction of fetal insulin levels was also associated with maternal DIMIT therapy in diabetic rabbits (56±5 (D) vs. 24±4 ,uU/ml, P < 0.001). Maternal diabetes resulted in significant reduction of fetal lung weight (370+20 vs. 520±30 mg, P < 0.005) and lung protein cont...
Transition of the epithelium of the fetal lung from fluid secretion to fluid reabsorption requires changes in the expression of ion channels. Corticosteroids regulate expression of several of these channels, including the epithelium sodium channel (ENaC) subunits and aquaporins (AQP). We investigated the ontogenetic changes in these ion channels in the ovine fetal lung during the last half of g...
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