OBJECTIVES The Ferula genus (Umbelliferae) is a rich source of gum-resin and is much utilized in folklore medicine. This study is designed to examine antioxidant and antihaemolytic activities of Ferula foetida regel flower, stem and leaf extracts. MATERIALS AND METHODS 1,1-Diphenyl-2-picryl hydrazyl radical (DPPH), nitric oxide and H2O2 scavenging activities, Fe2+ chelating ability, reducing ...

The medicinal plant Ferula has been widely used in Asian medicine, especially in Uyghur medicine in Xinjiang, China. Given that various substitutes and closely related species have similar morphological characteristics, Ferula is difficult to distinguish based on morphology alone, thereby causing confusion and threatening the safe use of Ferula. In this study, internal transcribed spacer 2 (ITS...

Objective: This study is to investigate the antioxidant and antitumor effects of the extract fractions of the Ferula sinkiangensis K. M. Shen. Methods: Four different fractions of the Ferula sinkiangensis K. M. Shen were obtained by the extraction with petroleum ether, ethyl acetate, n-butanol, and methanol, respectively, which were used to treat the HCT116, Caco-2, HepG2, and MFC cells. Free r...

Objective: In a previous work, we showed that asafoetida essential oil (AEO), from oleo-gum resin of Ferula asafoetida L. from the Apiaceae family, has a vasodilatory effect. This effect was both endothelium-dependent and endothelium-independent. The present study was designed to determine whether potassium channels and intracellular calcium release contribute to AEO-i...

Herbs and spices have been traditionally used for prevention and cure of many diseases. Hence, the present study was aimed to investigate the effects of aqueous and alcoholic extract of four different spices (asafoetida, ginger, cinnamon and cardamom) extracts on human breast adenocarcinoma cell line (MCF) and HEP-G2 cancer cell lines through in-vitro growth inhibitory assay. Both aqueous and a...